Subcutaneous Phaeohyphomycosis: A Clinical Mimic of Skin and Soft Tissue Neoplasms—A Descriptive Study from India

Jinkala, Sreerekha; Basu, Debdatta; Siddaraju, Neelaiah; Stephen, Norton; Hanuman, Srinivas Bheemanati; Singh, Rakesh

doi:10.1007/s00268-018-4745-0

Cited by 11 publications

(15 citation statements)

References 15 publications

(20 reference statements)

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“…Phaeohyphomycosis is a term used to denominate opportunistic, cutaneous and systemic infections [3]. The mainly genus are Wangiella , Alternaria and Exophiala .…”

Section: Introductionmentioning

confidence: 99%

Cutaneous phaeohyphomycosis caused by Exophiala xenobiotica: A case report

Espanhol

Recuero

Pagani

et al. 2020

Medical Mycology Case Reports

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We report a case of phaeohyphomycosis that affected the leg of a 45-year-old Brazilian man, car mechanic and renal transplanted. The direct mycological examination evidenced dematiaceous septated hyphae. The pathogenic fungal species was identified as Exophiala xenobiotica. Antifungal activity in vitro revealed terbinafine as the best antifungal. For treatment, it was chosen surgical excision of the entire lesion and used systemic itraconazole. Phaeohyphomycosis caused by Exophiala xenobiotica is extremely rare and is closely related to transplant patients.

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“…Phaeohyphomycosis is a term used to denominate opportunistic, cutaneous and systemic infections [3]. The mainly genus are Wangiella , Alternaria and Exophiala .…”

Section: Introductionmentioning

confidence: 99%

Cutaneous phaeohyphomycosis caused by Exophiala xenobiotica: A case report

Espanhol

Recuero

Pagani

et al. 2020

Medical Mycology Case Reports

View full text Add to dashboard Cite

show abstract

“…Hence it is clinically misdiagnosed as sebaceous cyst, ganglion cyst or lipoma. [5,6] In our scenario also cases were clinically misdiagnosed as sebaceous cyst as well as ganglion cyst, two of which had immunosuppressive conditions and one had a history of trauma.Histologically, subcutaneous form presents as pseudocystic space lined by granulation tissue, giant cell reaction along with hyphal fungal elements. Two cases were diagnosed by Fine needle aspiration cytology (FNAC).…”

Section: Discussionmentioning

confidence: 67%

More Than Just a Swelling: A Pathologist’s Perspective

B¹,

Devi²,

K³

et al. 2020

ATMPH

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Deep mycosis is commonly seen in immunocompromised individuals and rarely in immune competent patients but they have increased morbidity and mortality. These cases, when they present as skin lesions or subcutaneous swellings, are often misdiagnosed as sebaceous cyst or soft tissue tumors and the patients are often not treated properly. Here, we would like to present a series of deep mycosis cases which were clinically misdiagnosed as soft tissue lesions/tumors and the importance of fine needle aspiration cytology and diligent histopathological examination to aid in the proper care of patients.

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“…Phaeohyphomycosis is a group of infectious diseases caused by filamentous or darkly pigmented fungi. They are named dematiaceous or melanized due to the deposition of melanin in their cell walls [1][2][3][4] . We often find these fungi in nature, soil, wood, and decomposing plant debris in subtropical and tropical climates 2,[5][6][7] .…”

Section: Introductionmentioning

confidence: 99%

“…Phaeohyphomycosis usually develops through traumatic inoculation of the skin and subcutaneous tissue with contaminated matter, with most reports occurring on rural and outdoor workers 2,6 . The infection manifests in four clinical forms: superficial, subcutaneous, invasive (affecting brain, central nervous system, peritoneum, bones, and/or lungs), and systemic (funge mia) 2,4,9 . The subcutaneous form is the most common presentation.…”

Section: Introductionmentioning

confidence: 99%

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Cutaneous phaeohyphomycosis caused by <i>Exophiala dermatitidis</i> in an immunosuppressed patient: A case report and brief review

Bueno¹,

Ferreira²,

Severo³

et al. 2023

PJDV

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Phaeohyphomycosis is a group of fungal infections caused by filamentous dematiaceous fungi, which have melanin in their cell walls. Phaeohyphomycosis has four clinical forms: superficial, subcutaneous, systemic, and disseminated. Although rare, the subcutaneous form shows a significant prevalence in immunocompromised individuals, especially in solid organ transplant recipients. We report a case of subcutaneous phaeohyphomycosis in a renal transplant patient, caused by the species Exophiala dermatitidis. Although the case reveals characteristic clinical manifestations of the disease, laboratory and cultural findings were atypical. Based on this case of subcutaneous phaeohyphomycosis, a brief literature review is carried out on this rare and important fungal infection in medical practice.

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Subcutaneous Phaeohyphomycosis: A Clinical Mimic of Skin and Soft Tissue Neoplasms—A Descriptive Study from India

Abstract: Subcutaneous phaeohyphomycosis mimics benign skin and soft tissue neoplasms clinically. Histopathological examination along with cytology plays a major role in diagnosis of phaeohyphomycosis and thus helps in appropriate patient management.

Cited by 11 publications

References 15 publications

Cutaneous phaeohyphomycosis caused by Exophiala xenobiotica: A case report

Cutaneous phaeohyphomycosis caused by Exophiala xenobiotica: A case report

More Than Just a Swelling: A Pathologist’s Perspective

Cutaneous phaeohyphomycosis caused by <i>Exophiala dermatitidis</i> in an immunosuppressed patient: A case report and brief review

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