Subcutaneous panniculitis‐like T‐cell lymphoma in a young girl presenting with periorbital edema and fever: A case report

Abstract

Subcutaneous panniculitis‐like T‐cell lymphoma is a rare and highly malignant extra‐nodal lymphoma. It has a wide range of clinical presentations (such as periorbital swelling as in our case) and should be considered in the differential diagnosis of systemic lupus erythematosus, especially in children.

Subcutaneous Panniculitis-like T-Cell Lymphoma with a Transformation to Lupus Erythematosus Panniculitis: A Case Report

“…Constitutional symptoms such as fever, fatigue, and weight loss may be present [7]. Moreover, eyelid erythema and swelling, like in our case, is noted as the initial manifestation of SPTCL [8, 9]. In contrast, ulceration, lymph node and bone marrow involvement rarely occur [10, 11].…”

A Difficult-to-Diagnose Case of Subcutaneous Panniculitis-Like T-Cell Lymphoma with a Fatal Outcome

“…The other conditions which can have plaques and nodules with ulceration include lupus panniculitis, cytophagic histiocytic panniculitis, pancreatic panniculitis, nodular vasculitis, and erythema nodosum leprosum. Clinically and histopathologically, SPTCL is difficult to distinguish from lupus erythematosus panniculitis[ 2 ] and can be misinterpreted. In HPE, the rimming of certain fat compartments by neoplastic cells is the distinctive feature of SPTCL that is present in our case [ Figure 5 ], suggesting that this lymphoma had a peculiar tropism for adipocytes[ 3 ].…”