Subcutaneous lidocaine delivered by jet-injector for pain control before IV catheterization in the ED: The patients' perception and preference

Peter, David J.; Scott, John; Watkins, Henry C.; Frasure, Heidi E.

doi:10.1053/ajem.2002.35493

Cited by 14 publications

(7 citation statements)

References 23 publications

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“…3 The jet device has proven to be both safe and effective during its use to administer vaccinations and a variety of other pharmaceuticals. [4][5][6] It does not contain any sharps, thereby reducing the risk of needle-stick injuries, and it can be safely discarded in a normal waste container.…”

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confidence: 99%

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A Randomized, Double‐blind Controlled Study of Jet Lidocaine Compared to Jet Placebo for Pain Relief in Children Undergoing Needle Insertion in the Emergency Department

Auerbach

Tunik

Mojica

2009

Academic Emergency Medicine

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Objectives: The objectives were to determine whether pretreatment with needleless jet-delivered lidocaine decreases self-reported pain in children undergoing needle insertion in the emergency department (ED) and to explore whether pretreatment with a jet device decreases self-reported pain in children undergoing needle insertion in the ED.Methods: This study examined needle insertion pain in children 5-18 years of age. In the first phase of this study, children received either pretreatment with jet-delivered lidocaine (0.2 mL of buffered 1% lidocaine; n = 75) or pretreatment with jet-delivered placebo (0.2 mL of preservative-free normal saline; n = 75) 60 seconds before undergoing needle insertion. This phase of the study had a randomized, double-blind, placebo-controlled design. In the second phase, an unblinded, nonconcurrent, nonintervention control group (n = 47) was examined to describe any effect of using the jet device. Patients reported pain upon administration of the jet device and at needle insertion using a 100-mm color analog scale (CAS). Patients also reported their satisfaction with this device. The physicians and nurses performing needle insertions were asked to rate their ability to visualize the vein and their satisfaction with the device.

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confidence: 99%

“…9,10 A randomized, single-blind placebo-controlled study in adults noted a reduction in pain in the jet lidocaine group. 4 Another randomized, double-blind trial compared jet lidocaine to jet placebo and a nonintervention control group in adults. This study revealed a significant reduction in pain for the jet lidocaine group.…”

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confidence: 99%

A Randomized, Double‐blind Controlled Study of Jet Lidocaine Compared to Jet Placebo for Pain Relief in Children Undergoing Needle Insertion in the Emergency Department

Auerbach

Tunik

Mojica

2009

Academic Emergency Medicine

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“…Peter et al. also reported no difference of pain perception between groups of children that had subcutaneous lidocaine or not before venous catheterization. In our study, children who were passive smokers had a lower pain threshold/significantly heightened pain perception than nonpassive smokers.…”

Section: Discussionmentioning

confidence: 97%

Passive smoking increases pain perception in children undergoing venous catheterization

et al. 2013

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“…Liquid jet injectors have been shown to successfully deliver insulin [292], lidocaine [293,294] vaccines [290], human growth hormone [295], midazolam [296], bleomycin [297], interferon [298] and erythropoietin [299]. Needle-free liquid jet injectors have been associated with frequent bruising and pain, which offsets their advantages over the conventional needle and syringe approach [290].…”

Section: Jet Injectionmentioning

confidence: 99%

Innovative Strategies for Enhancing Topical and Transdermal Drug Delivery

Morrow¹,

McCarron²,

Woolfson³

et al. 2007

TODDJ

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Abstact: Historically, the skin was thought to be a simple homogenous barrier. However, it is now known to be a highly specialised organ, and plays a key role in homeostasis. The protective properties of the skin are provided by the outermost layer, the epidermis, which safeguards against chemical, microbial, and physical attack. The exceptional barrier properties of the skin result in it being a challenging route for the delivery of therapeutic agents. This article reviews strategies developed to enhance the skin penetration of drugs, ranging from conventional approaches, for example the use of chemical penetration enhancers to those in early-stage development, such as microscissioning.

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Subcutaneous lidocaine delivered by jet-injector for pain control before IV catheterization in the ED: The patients' perception and preference

Cited by 14 publications

References 23 publications

A Randomized, Double‐blind Controlled Study of Jet Lidocaine Compared to Jet Placebo for Pain Relief in Children Undergoing Needle Insertion in the Emergency Department

A Randomized, Double‐blind Controlled Study of Jet Lidocaine Compared to Jet Placebo for Pain Relief in Children Undergoing Needle Insertion in the Emergency Department

Passive smoking increases pain perception in children undergoing venous catheterization

Innovative Strategies for Enhancing Topical and Transdermal Drug Delivery

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