Subcutaneous implantation of metastatic carcinoma: An unpredicted event following endoscopic parathroidectomy for adenoma

Parathyromatosis—A rare occurrence along the endoscopic tract detected on fine needle aspiration cytology

“…4 Ectopic sites such as mediastinum, thyroid, and retro-oesophageal have been described. 1,5 Parathyromatosis may be primary in cases with multiple endocrine neoplasia syndromes. With prolonged hyperparathyroid state, other complications like bony and muscular pains, renal stones, and pathological fractures can occur.…”

“…The usual presenting symptoms are weakness, anorexia, fatigue, nausea, polyuria, polydipsia, dyspepsia, loss of weight, and constipation. Bhattacharya et al 5 described a case of parathyroid carcinoma with metastasis in the endoscopic parathyroidectomy tract. 4 Parathyromatosis is the occurrence of hyperfunctioning parathyroid tissue in areas of neck or mediastinum, few cases of which have been described in literature.…”

“…4 Parathyromatosis is the occurrence of hyperfunctioning parathyroid tissue in areas of neck or mediastinum, few cases of which have been described in literature. 1,5 Parathyromatosis may be primary in cases with multiple endocrine neoplasia syndromes. Secondary parathyromatosis has been described in cases with prior parathyroidectomy due to spillage of parathyroid tissue during open surgery for parathyroid adenoma resulting in recurrent hyperparathyroidism 1,2 ; however, to our knowledge, parathyroid seedlings along the endoscopic tract in a patient with parathyroid adenoma has not been described in literature.…”

“…Secondary parathyromatosis has been described in cases with prior parathyroidectomy due to spillage of parathyroid tissue during open surgery for parathyroid adenoma resulting in recurrent hyperparathyroidism 1,2 ; however, to our knowledge, parathyroid seedlings along the endoscopic tract in a patient with parathyroid adenoma has not been described in literature. Bhattacharya et al 5 described a case of parathyroid carcinoma with metastasis in the endoscopic parathyroidectomy tract. Contiguous infiltration into thyroid was also seen in this case.…”

“…Contiguous infiltration into thyroid was also seen in this case. 5 Implantation of tumor seedlings along the needle tract has also been described after FNAC in parathyroid carcinoma. 6,7 In the present case, parathyroid tissue was detected on FNAC and confirmed on immunocytochemistry.…”