Subcutaneous fibroadenoma on an arm

Amazon, Kip; Glick, Harold

doi:10.1097/00000372-198504000-00005

Cited by 12 publications

(6 citation statements)

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“…Apocrine metaplasia, squamous metaplasia, or intraductal epithelial hyperplasia may be seen occasionally. The nonepithelial components show variable degrees of cellularity and collagenization 3 …”

Section: Discussionmentioning

confidence: 99%

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Fibroadenoma of the Axilla

Coras

Landthaler

Hofstaedter

et al. 2006

Dermatologic Surgery

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Section: Discussionmentioning

confidence: 99%

“…It is subject to all disease processes that affect the normal breast, including cancer 2 . Fibroadenomas are the most common benign neoplasms of the breast, generally appearing as well‐circumscribed, painless masses in young women 3 …”

mentioning

confidence: 99%

Fibroadenoma of the Axilla

Coras

Landthaler

Hofstaedter

et al. 2006

Dermatologic Surgery

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“…These glands were regarded by most as anogenital "sweat" glands with histological appearance mimicking that of mammary glands. 6 Supernumerary breast tissue has been reported outside the milk line in the shoulder, back, arms, and legs. These mammary-like anogenital glands express hormone receptors detected by immunohistochemistry.…”

Section: Discussionmentioning

confidence: 99%

“…These mammary-like anogenital glands express hormone receptors detected by immunohistochemistry. 2,5,6 It may be that these neoplasms arise from local eccrine glands transformed to apocrine glands with the ability to form acini-like mammary glands. 11 Other than the fibroadenomas found in the anogenital region, to our knowledge, there have only been 5 reported cases (including the current case) of fibroadenomas elsewhere in the body (Table 1).…”

Section: Discussionmentioning

confidence: 99%

Apocrine Fibroadenoma on the Face

Khalsa

Conway

Heaney

et al. 2016

The American Journal of Dermatopathology

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Apocrine fibroadenoma (AFA) is a common benign entity found in the breast but is rarely seen at other sites. Several studies have documented cases in the anogenital region, but to date, there have been only 4 cases (excluding the current case) of an AFA located in the skin on other parts of the body. The authors present a case of a 66-year-old woman with a 6-year history of a slow growing red nodule on her face. The histopathologic diagnosis was consistent with an AFA. An extensive review of the literature to elucidate a possible pathogenesis of these lesions and relationship to the anogenital counterparts is presented.

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“…The arm and eyelid are the only other sites at which AFA is documented. 8,9 AFA occurs almost exclusively in women. Here we describe an AFA occurring on the face of a 75-year-old man and discuss its possible histopathogenesis.…”

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confidence: 99%

Facial Apocrine Fibroadenoma in Man: A Rare Finding

Liu¹,

Chang²,

Chen³

et al. 2007

The American Journal of Dermatopathology

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Apocrine fibroadenoma (AFA), considered a counterpart of fibroadenoma of breast, is a rare cutaneous apocrine neoplasm occurring almost exclusively in women. We describe a 75-year-old man who presented with a red dome-shaped papule near the nasal bridge. The tumor was composed of numerous tubular, cystic, and partially branching lumina and struts of epithelial cells oriented perpendicular to the skin surface, with which it connected through infundibula. The epithelial strands were embedded in fibrocollagenous stroma. These histopathological features are consistent with AFA. The cytokeratin profiles of our case were similar to those of apocrine or eccrine neoplasms. Progesterone and estrogen receptors (PR/ER) were not expressed. The stroma cells were stained strongly positive for vimentin, but nonreactive for alpha-smooth muscle actin, S-100 protein, or glial fibrillary acidic protein. To the best of our knowledge, this is the first report of facial AFA in man. Different from a more common anogenital AFA, this neoplasm might represent a second type of AFA with unique histopathologic and immunopathological features.

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Subcutaneous fibroadenoma on an arm

Cited by 12 publications

References 0 publications

Fibroadenoma of the Axilla

Fibroadenoma of the Axilla

Apocrine Fibroadenoma on the Face

Facial Apocrine Fibroadenoma in Man: A Rare Finding

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