Subcutaneous Carboxytherapy Injection for Aesthetic Improvement of Scars

Nach, Raphael; Zandifar, Hootan; Gupta, Reena; Hamilton, J. F.

doi:10.1002/lary.21318

Cited by 9 publications

(12 citation statements)

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“…Although carboxytherapy is widely used in many fields, only a few researches concerning its application in aesthetic medicine were published. It was discovered that it improves skin elasticity, circulation, aids collagen repair and destroys localized fatty deposits [18] . In the current study, the degree of improvement of PODC treated with chemical peeling in group A was found to be excellent in 46.7% of the patients, while showing good and fair result in 46.7% and 6.6% of them, respectively.…”

Section: Discussionmentioning

confidence: 99%

Treatment of Periorbital dark circles: Comparative study of chemical peeling with a combination of trichloroacetic acid and lactic acid versus carboxytherapy

Hassan¹,

Aldalies²,

Maghraby³

2016

J Surg Dermatol

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Periorbital dark circles (PODC) are a common worldwide cosmetic problem. It is difficult to treat due to complications in its pathogenesis and aetiology. Available lines of treatment for PODC include whitening creams, topical retinoid acid, chemical peeling, laser therapy, carboxytherapy, autologous fat transplantation, injectable fillers and surgery (blepharoplasty).The aim of this study isto evaluate and compare the efficacy of chemical peels using trichloroacetic acid (3.75%) and lactic acid (15%) in a gel formula with that of carboxytherapy, in the treatment of periorbital hyperpigmentation.Two groups of patients with PODC were included in the study, named Group A and B in which each group consisted of 15 patients. Group A was assigned for patients who received treatment with chemical peeling with a combination of trichloroacetic acid (3.75%) and lactic acid (15%) in a gel formula, once a week for four weeks. Group B was assigned for patients who received carboxytherapy that was performed by subcutaneous and intradermal injection of CO 2 once a week for four weeks. All patients were assessed by digital photographs, before and after treatment, by observing the improvement in the grade of PODC. Reports of patient satisfaction and global tolerance were evaluated by three medical observers. There was a significant improvement in the grade of PODC in both groups. The degree of improvement of PODC in group A was excellent, with good grade in 93.4% of the treated patients while fair grade in 6.6% of them. There was a statistically significant improvement in the pigmented type. The degree of improvement of PODC in group B was excellent, with good grade in 86.7% of the treated patients while fair grade in 13.3% of them. However, no statistically significant difference between the two groups was observed. Minimal and transient side effects were noticed; however, it did not require further treatment. In conclusion, the two methods of treatment were effective in the treatment of PODC, with the improvement of PODC observed from the first treatment session with both chemical peeling and carboxytherapy.

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Section: Discussionmentioning

confidence: 99%

Treatment of Periorbital dark circles: Comparative study of chemical peeling with a combination of trichloroacetic acid and lactic acid versus carboxytherapy

Hassan¹,

Aldalies²,

Maghraby³

2016

J Surg Dermatol

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“…Therapeutic indications of CO 2 therapy include vascular, cardiac, metabolic and rheumatic diseases, cellulite, chronic wounds, localized adiposities, migraine headaches. It is used, as well, in radiology to guided catheters placement and in laparoscopic surgeries for visualization of the surgical field [3][4][5][6][8][9][10][11][12][13][14][15][16][17] . CO 2 therapy is safe, with low cost, no toxicity or side effects [3][4][5]12,17 .…”

Section: Introductionmentioning

confidence: 99%

The effect of carbon dioxide therapy on composite graft survival

Duraes

Carneiro

et al. 2013

Acta Cir. Bras.

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PURPOSE:To investigate the effect of carboxytherapy in auricular composite grafts in rabbits. METHODS:An experimental study was conducted using 20 rabbits randomly assigned to a treatment group of carboxytherapy or a control group of saline solution. In each ear, a circular graft with 1.5 cm or 2 cm of diameter was amputated and reattached. Animals underwent carbon dioxide or saline injection four times during the experiment. We analyzed clinical evolution of the animals, grafts survival, histopathology features and histomorphometry of collagen. RESULTS:The treated group had a significantly lower weight gain (p=0.038). Histopathology was not significantly different between groups. There was an increase in amount of collagen in 2 cm grafts submitted to carbon dioxide therapy (p=0.003). Carboxytherapy didn't influence graft survival rate for 1.5 cm grafts or 2 cm grafts (p=0.567 and p=0.777, respectively). CONCLUSIONS:Carbon dioxide therapy increased the amount of collagen in 2 cm grafts. CO 2 was not significantly different from saline infusion on composite grafts survival, but this study suggests that there is a mechanical effect caused by distension which favored graft survival.

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“…Subcision with CO 2 infusion allows for reach beyond the length of the needle is an advantage for larger scars, this is akin to the same principle when Carbon Dioxide therapy is being used for reducing irregularity from liposuction [4] and cellulite [7,13]. The distension of the tissue caused by the gas triggers tissue repair and regeneration processes with neovascularization and remodeling of the extracellular matrix [7] and this contributes to the final results of the scars being treated [10,14,15].…”

Section: Discussionmentioning

confidence: 99%

“…Carboxytherapy has been used to treat localised adiposity [3], post liposuction irregularity [4], chronic wounds [5], skin laxity, cellulite [6][7], striae [8] dark under circles [9], and scars [10]. CO 2 therapy is administered subcutaneously for lipolysis [3] or intradermally using a programmable CO 2 therapy apparatus (Carbomed®, Carbossi Italy) and disposable 32G needles.…”

Section: Introductionmentioning

confidence: 99%

Carbon Dioxide Assisted Subcision in the Treatment of Adherent Localized Scars

Sk¹

2018

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Abstract:Modified subcision assisted with Carbon Dioxide insufflation is described in 2 patients; one with post acne scar and another with adhesion following liposuction. Both subjects have satisfactory results after 3 fortnightly sessions. The Carbon Dioxide flow controlled by the flow rate and procedurist's maneuvering adjusted to the size and positon of the scars help to separate the underlying fibrotic bands allowing the reach beyond the length of the subcising device; in this case being a 30G ½ needle. The results and recovery is being compared with traditional subcision and possible benefits of Carbon Dioxide assisted subcision are discussed.

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Subcutaneous Carboxytherapy Injection for Aesthetic Improvement of Scars

Cited by 9 publications

References 0 publications

Treatment of Periorbital dark circles: Comparative study of chemical peeling with a combination of trichloroacetic acid and lactic acid versus carboxytherapy

Treatment of Periorbital dark circles: Comparative study of chemical peeling with a combination of trichloroacetic acid and lactic acid versus carboxytherapy

The effect of carbon dioxide therapy on composite graft survival

Carbon Dioxide Assisted Subcision in the Treatment of Adherent Localized Scars

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