Subcutaneous and Intranasal Administration of 1-Deamino-8-&lt;i&gt;d&lt;/i&gt;-Arginine Vasopressin in the Assessment of Renal Concentration Capacity

Tryding, Nils; Sterner, Gunnar; Berg, Bertel; Harris, Alice C.; Lundin, S.

doi:10.1159/000184066

Cited by 26 publications

(19 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The age related normal value for maximal concentration ability after Minirin@ is about 900mOsm/kg in the patients of the present study (17). The mean value of the maximal concentration ability in our patients was 671 mOsm/kg.…”

Section: Scand J Urol Nephrol28supporting

confidence: 47%

Influence of pH on Reservoir Mucosal Absorption/-Secretion and Tubular and Glomerular Function. Studies in Patients with a Continent Ileal Reservoir for Urinary Diversion

Åkerlund

Campanello

Herlitz

et al. 1994

Scandinavian Journal of Urology and Nephrology

View full text Add to dashboard Cite

Ten patients with a continent ileal reservoir for urinary diversion were studied regarding transmucosal fluxes of water and electrolytes at different pH. The urine was by-passed the reservoir via a Foley catheter. The experiment set-up was designed to exclude urine from reservoir mucosa exposition during the study. Test solutions of pH 4 and pH 7 with electrolytes and a non-absorbable volume marker (PEG MW 4000) were instilled into the empty reservoir. The influence of altered pH on the flow of water and Na,+K+ and Cl- across the reservoir mucosa was analysed. The maximal concentration ability after intranasal desmopressin (Minirin), the creatinine and Na-clearance as well as the fractional Na-excretion were calculated from measurements on the by-passed urine. The results showed a secretion of water, Na+ and Cl- into the reservoir while the K+ content was constant. The mucosal flows of water and electrolytes were not affected by alterations in reservoir pH. Maximal concentration ability appeared to be reduced compared to normals. Fractional Na excretion was within normal limits.

show abstract

Section: Scand J Urol Nephrol28supporting

confidence: 47%

Influence of pH on Reservoir Mucosal Absorption/-Secretion and Tubular and Glomerular Function. Studies in Patients with a Continent Ileal Reservoir for Urinary Diversion

Åkerlund

Campanello

Herlitz

et al. 1994

Scandinavian Journal of Urology and Nephrology

View full text Add to dashboard Cite

show abstract

“…A baseline sample (T₀) was collected before the administration of an intranasal spray of DDAVP (desmopressin acetate, 20 µg) [16] and a second sample was collected 4 h later (T 4 ). The U/P osm ratio was calculated and a value less than 2.8 was considered abnormal.…”

Section: Methodsmentioning

confidence: 99%

Renal Function Improvement with Pentavalent Antimonial Agents in Patients with Visceral Leishmaniasis

Daher

Rocha²,

Oliveira

et al. 2011

Am J Nephrol

View full text Add to dashboard Cite

Background: The aim of this study is to investigate tubular and glomerular function after visceral leishmaniasis (VL) treatment with pentavalent antimonials. Methods: This is a prospective study including 14 patients with VL diagnosis treated with pentavalent antimonials. Urine acidification and concentration tests were performed. Estimated glomerular filtration rate (eGFR), fractional excretion of sodium (FE_Na) and potassium (FE_K) and free water clearance (C_H2O) were measured to assess glomerular and tubular function. Results: The VL group had a significantly lower FE_K, serum sodium and plasma osmolality (P_osm). No significant differences were found regarding proteinuria, eGFR, FE_Na or C_H2O. Patients in the VL group had lower urinary osmolality (U_osm) before DDAVP use when compared to the control group, as well as a lower U/P_osm. The urinary pH before and after CaCl₂ load was higher in the VL group. Conclusion: This study shows evidence of reversal of some tubular dysfunction in VL, but other dysfunctions may persist, especially urinary acidification capacity.

show abstract

“…The ability to concentrate urine within the collecting ducts of the nephrons was investigated by the subcutaneous administration of 4 pg of desmopressin (Tryding et al 1987). The desmopressin test (DT) was performed preoperatively, as well as postoperatively within 2 days after the GFR determination.…”

Section: Methodsmentioning

confidence: 99%

Renal function not Impaired by hip arthroplasty

Stegmayr

Björck²,

Kempi³

et al. 1992

Acta Orthopaedica Scandinavica

View full text Add to dashboard Cite

Subcutaneous and Intranasal Administration of 1-Deamino-8-<i>d</i>-Arginine Vasopressin in the Assessment of Renal Concentration Capacity

Cited by 26 publications

References 6 publications

Influence of pH on Reservoir Mucosal Absorption/-Secretion and Tubular and Glomerular Function. Studies in Patients with a Continent Ileal Reservoir for Urinary Diversion

Influence of pH on Reservoir Mucosal Absorption/-Secretion and Tubular and Glomerular Function. Studies in Patients with a Continent Ileal Reservoir for Urinary Diversion

Renal Function Improvement with Pentavalent Antimonial Agents in Patients with Visceral Leishmaniasis

Renal function not Impaired by hip arthroplasty

Contact Info

Product

Resources

About