Subclinical Atherosclerosis in Behçet’s Disease

Hassan, Samia Z.; Gheita, Tamer A.; Ghoneim, Sherine; Nasr, Loi

doi:10.5606/tjr.2012.016

Cited by 30 publications

(26 citation statements)

References 32 publications

(34 reference statements)

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“…1), 24 studies met the criteria for inclusion in the analysis: 9 investigated FMD and/or EMD [18][19][20][21][22][23][24][25][26], 11 IMT [8,[27][28][29][30][31][32][33][34][35][36] and 4 investigated both [37][38][39][40].…”

Section: Resultsmentioning

confidence: 99%

“…All investigators measured IMT at the common carotid artery but for one study where the authors presented the average IMT taken at the distal common carotids, at the far wall of the carotid bulbs and at the far wall of the internal carotid artery [8]. Indeed studies varied with regards to inclusion criteria: n ¼ 3 compared patients with and without vascular involvement and provided separate measurements [27,37,38], n ¼ 1 provided separate data for patients with and without systemic involvement (mucocutaneous only) [36], n ¼ 3 studies included a mixture of active and inactive disease [32,34,40] of which one provided separate data for active and inactive disease [32], n ¼ 3 studies were carried out on patients with low or inactive disease [31,33,35], n ¼ 2 were carried out on patients without vascular and/or systemic involvement [38,39] and n ¼ 2 were carried out in patients without cardiovascular risk factors [28,30].…”

Section: Analysis Of Intima Media Thickness Of Carotid Arteriesmentioning

confidence: 99%

See 1 more Smart Citation

Subclinical atherosclerosis in Behcet’s disease: A systematic review and meta-analysis

Merashli¹,

Ster

Ames

2016

Seminars in Arthritis and Rheumatism

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Section: Resultsmentioning

confidence: 99%

Section: Analysis Of Intima Media Thickness Of Carotid Arteriesmentioning

confidence: 99%

Subclinical atherosclerosis in Behcet’s disease: A systematic review and meta-analysis

Merashli¹,

Ster

Ames

2016

Seminars in Arthritis and Rheumatism

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“…The role of duplex scanning in the investigation of carotid artery disease is well established, and there is evidence to suggest that it has a predictive role in identifying those patients with a greater than normal risk of stroke [5]. The study of the IMT in other rheumatic diseases on Egyptian patients showed subclinical atherosclerosis in rheumatoid arthritis [9], systemic lupus erythematosus [10], Behc¸ets disease [11] and primary osteoarthritis [12].…”

Section: Introductionmentioning

confidence: 97%

Subclinical atherosclerosis and peripheral vascular disease in systemic sclerosis patients: Relation to potential risk factors

Farag

Serougy

Metawee

et al. 2015

The Egyptian Rheumatologist

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Aim of the work: To measure the extent of subclinical atherosclerosis in patients with systemic sclerosis, and to evaluate any potential vascular risk factors in these patients.Patients and methods: This study included 30 patients with systemic sclerosis diagnosed according to the American college of rheumatology criteria and 20 healthy individuals were also included as a control group. Non-invasive vascular tests including; carotid duplex scanning measuring common carotid arteries (CCA) intima-media thickness (IMT), and ankle brachial pressure index (ABPI) were performed. Traditional vascular risk factors such as blood pressure, blood sugar, lipid profiles, steroid usage and other immunosuppressive medications were assessed.Results: The mean IMT of CCA was higher in systemic sclerosis patients (right 0.67 ± 0.11 mm, left 0.67 ± 0.12 mm) when compared with the control group (right 0.48 ± 0.2 mm, left 0.54 ± 0.13 mm) (p < 0.001). Carotid plaques were found in 4 SSc patients. Mean IMT was correlated with patients' age (p < 0.001), disease duration (p < 0.001), systolic blood pressure (p < 0.05), and dyslipidemia (p < 0.01). Ankle brachial pressure index (ABPI) was significantly lower in SSc patients (0.94 ± 0.13) when compared with controls (1.16 ± 0.12) (p < 0.001). No difference was found between limited (n = 25) and diffuse (n = 5) disease subtypes in mean IMT, nor in mean ABPI. There was no significant correlation between mean IMT and steroid dose or other immunosuppressive intake.Conclusion: There is an increased risk of subclinical atherosclerosis and peripheral arterial disease in SSc patients. Increased systolic blood pressure, dyslipidemia, long disease duration and older age were possible risk factors.

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“…In another study on Egyptian BD patients, a morphologic evidence of subclinical carotid artery atherosclerosis was verified and the disease activity significantly suggested cardiovascular involvement. [18].…”

Section: Introductionmentioning

confidence: 95%

Assessment of left ventricular function and aortic elastic properties in patients with Behçet’s disease using conventional and tissue Doppler echocardiography

Hassan

Ebaid

2016

The Egyptian Rheumatologist

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Background: Behc¸et disease (BD) is a multisystemic, chronic inflammatory disorder of unknown etiology with diffuse clinical manifestations including the cardiovascular system.Aim of the work: To assess left ventricular (LV) function and thoracic aorta elastic properties in BD patients using Doppler echocardiography and to correlate echocardiographic findings with disease activity.Patients and methods: The LV functions and thoracic aorta elastic properties were assessed in 30 BD patients and 30 controls using conventional and Tissue Doppler Imaging (TDI) echocardiography. Disease activity was evaluated using Behc¸et's disease current activity form (BDCAF). Erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), cholesterol and triglyceride levels were measured.Results: In BD patients, ESR and CRP were significantly elevated while cholesterol and triglycerides were comparable to the levels in the control. In conventional echocardiography, BD patients had significantly higher aortic diastolic diameter (p < 0.05), aortic stiffness index (p < 0.001), isovolumic relaxation time (p < 0.001), flow propagation velocity (FPV) and peak E-wave velocity/FPV (E/FPV) (p < 0.001) than the control group while aortic strain was significantly lower

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Subclinical Atherosclerosis in Behçet’s Disease

Cited by 30 publications

References 32 publications

Subclinical atherosclerosis in Behcet’s disease: A systematic review and meta-analysis

Subclinical atherosclerosis in Behcet’s disease: A systematic review and meta-analysis

Subclinical atherosclerosis and peripheral vascular disease in systemic sclerosis patients: Relation to potential risk factors

Assessment of left ventricular function and aortic elastic properties in patients with Behçet’s disease using conventional and tissue Doppler echocardiography

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