Abstract:Citation: Tashev R, Stavreva GT, Velikova MS. Subchronic central administration of cannabinoid ligands modulates nociception in bulbectomized rats. Folia Med (Plovdiv) 2019;61(4):540-4.Abstract Introduction: Endocannabinoid system is involved in neuropsychiatric disorders such as major depression. The bilaterally olfactory bulbectomized rat is widely used as an animal model of depression. The removal of the olfactory bulbs produces behavioural, physiological, and neurochemical alterations resembling clinical d… Show more
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