Abstract:Dopamine neurons use autoregulation for appropriate modulation of goal-directed behaviors, and yet the mechanisms for D2 receptor (D2R)-mediated autoregulation are not fully understood. Electrophysiology suggests close proximity between dopamine release and receipt, but actual dendro-dendritic synapses are rare. This ultrastructural study used transgenic mice with a knockin of superecliptic green fluorescent protein (SEP) on the D2R (SEP-D2R) to determine how often autoreceptors are localized at directly appos… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.