Subcapsular Orchiectomy under Local Anaesthesia Technique, Results and Implications

Desmond, A. D.; Arnold, A.; Hastie, K. J.

doi:10.1111/j.1464-410x.1988.tb05063.x

Cited by 28 publications

(8 citation statements)

References 4 publications

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“…In their study of 74 patients, Zhang et al (7) reported complications rates of 3% and 22% respectively for patients undergoing subcapsular and total orchiectomy, and similar rates have been confirmed in numerous other studies (8,9). These studies have generally shown that the subcapsular technique has fewer complications.…”

Section: Discussionsupporting

confidence: 59%

Comparison of Subcapsular and Total Orchiectomy in Patients with Prostate Cancer

Yıkılmaz¹,

Öztürk²,

Hamidi³

et al. 2018

uob

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Objective: We aimed to compare the oncologic and functional outcomes of patients who underwent subcapsular or total orchiectomy for surgical castration in prostate cancer. Materials and Methods:We studied 65 patients who underwent total or subcapsular orchiectomy with a diagnosis of prostate cancer between April 2014 and May 2017. At postoperative 3-month follow-up, prostate specific antigen (PSA) and total testosterone levels were measured and patients were asked about their psychological status due to organ loss. Results were compared between the groups. Results: Sixty-five patients were evaluable: 23 had subcapsular and 42 had total orchiectomy. The mean age of the cases was 71.4 (60-83) years, the mean PSA level was 45.4 ng/dL (4-3800 ng/dL), and 41 cases had metastatic foci. There was no significant difference between the complication rates of the groups, but duration of the operation was significantly shorter in the subcapsular orchiectomy group. The two groups had similar mean PSA and testosterone levels at postoperative 3 months, but significantly more patients with total orchiectomy reported psychological problems due to organ loss. Conclusion: Subcapsular orchiectomy should be preferred for surgical castration because of the short duration of operation and the advantage of organ presence within the scrotal sac after surgery. In terms of oncologic outcomes, subcapsular orchiectomy shows no difference from total orchiectomy and is a safe alternative. Keywords: Subcapsular orchiectomy, total orchiectomy, prostate cancer

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Section: Discussionsupporting

confidence: 59%

Comparison of Subcapsular and Total Orchiectomy in Patients with Prostate Cancer

Yıkılmaz¹,

Öztürk²,

Hamidi³

et al. 2018

uob

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“…Desmond et al [8] found complications that prolonged hospital stay in 8% of 100 patients who underwent subcapsular orchiectomy under local anesthesia. Using a CO 2 laser and subcapsular orchiectomy, Wishnow and Johnson [9] had one postoperative complication among 13 patients, and Rosemberg [10] reported one complication among 10 patients.…”

Section: Discussionmentioning

confidence: 98%

Subcapsular versus total orchiectomy in the treatment of advanced prostate cancer: A randomized trial

Roosen

Klarskov

Mogensen

2005

Scandinavian Journal of Urology and Nephrology

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“…However, use of chemical ADT was significantly higher among NHW men (80% vs 71%) while NHB men were significantly more likely to elect to have an orchiectomy (10% vs 6%). Given that orchiectomy results in permanent castration levels of testosterone, one explanation for racial differences in the type of ADT elected could include the potential for more aggressive disease progression in NHB men where orchiectomy might be considered a more effective and complete suppression of testosterone . It is also possible that NHB men and their physicians elect orchiectomy out of convenience if they have significant barriers, including economic, to regular, frequent visits to receive GnRH injections required as part of long‐term treatment.…”

Section: Discussionmentioning

confidence: 99%

Racial differences in patterns of treatment among men diagnosed with de novo advanced prostate cancer: A SEER‐Medicare investigation

et al. 2019

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Purpose Approximately 5% of men were initially diagnosed with (also referred to as de novo) advanced stage prostate cancer and experience far poorer survival compared to men diagnosed with local or regionally advanced disease. Given the number of new therapies targeting metastatic and castrate‐resistant disease, we sought to describe recent treatment patterns by race for de novo AJCC stage IV prostate cancer. Methods We used Surveillance, Epidemiology, and End Results (SEER) data linked to Medicare files to identify men aged 66 and older diagnosed in 2004‐2014 with advanced prostate cancer, and examined patterns of treatment among all patients and stratified by race/ethnicity. Results There were 8828 eligible patients identified, and non‐Hispanic black (NHB) patients were more likely to go without treatment (P < 0.001) compared to non‐Hispanic white (NHW) patients, even after accounting for early mortality and TNM stage. The frequency of nearly all forms of treatment was lower among NHB with the exception of orchiectomy, which was significantly higher (10.1% vs 6.1%, P < 0.001), and the use of the progesterone Megace among Medicare Part D enrollees (24.6% vs 15.0%, P < 0.001). Conclusions Results from this study of elderly Medicare patients presenting with advanced stage prostate cancer suggest that NHB men are less likely to pursue aggressive treatment options. With the reduction in screening for prostate cancer, presumably tied to USPSTF recommendations, and the increasing incidence of men diagnosed with de novo metastatic disease, understanding drivers of treatment‐related decisions are critical in reducing racial disparities in advanced prostate cancer outcomes.

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Subcapsular Orchiectomy under Local Anaesthesia Technique, Results and Implications

Cited by 28 publications

References 4 publications

Comparison of Subcapsular and Total Orchiectomy in Patients with Prostate Cancer

Comparison of Subcapsular and Total Orchiectomy in Patients with Prostate Cancer

Subcapsular versus total orchiectomy in the treatment of advanced prostate cancer: A randomized trial

Racial differences in patterns of treatment among men diagnosed with de novo advanced prostate cancer: A SEER‐Medicare investigation

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