Subacute thyroiditis with airway compromise in a 5-year-old boy

Ramineni, Pardha; Kamath, Shobha; Joshi, Jayateertha; Rao, Shama

doi:10.1136/bcr-2020-236909

Cited by 5 publications

(8 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Consider thyroid hormone testing and/or other SAT screening methods especially in ICU patients 2. Possible occurrence in young children [ 31 , 32 ] 2. Physicians should be aware about possible SAT occurrence in children; possible atypical course with trachea compression [ 31 ] Clinical course 1.…”

Section: Discussionmentioning

confidence: 99%

“…Possible occurrence in young children [ 31 , 32 ] 2. Physicians should be aware about possible SAT occurrence in children; possible atypical course with trachea compression [ 31 ] Clinical course 1. More frequent painless course: • >6% in Caucasian population [ 29 ] 1.…”

Section: Discussionmentioning

confidence: 99%

“…However, the symptoms of SAT were present in as many as 10–20% of patients hospitalized due to COVID-19 on intensive care units (ICU) and non-intensive care units, respectively [ 18 , 30 ]. Moreover, recently young children affected by SAT have been reported [ 31 , 32 ]. Thus, the clinicians should be aware of a possible presence of SAT in children, including the youngest ones.…”

Section: Epidemiologymentioning

confidence: 99%

“…As it was previously mentioned, some cases of children with SAT have been reported [ 31 , 32 ]. The most spectacular case, published very recently, regarded 5-year-old boy with airway compromise caused by SAT [ 31 ]. The boy suffered from fever, painful neck swelling, dysphagia and hoarseness for a few weeks and finally he was admitted to hospital due to dyspnea.…”

Section: Current Clinical Manifestation and Factors Modifying Clinical Coursementioning

confidence: 99%

“…US and fine needle aspiration biopsy (FNAB) findings were typical for SAT and magnetic resonance imaging confirmed trachea compression by the enlarged thyroid. Steroid treatment led to symptom resolution [ 31 ]. Thus, one should remember about the possibility of SAT occurrence in children, as well as of the fact that symptoms of airway compression may be a manifestation of SAT.…”

Section: Current Clinical Manifestation and Factors Modifying Clinical Coursementioning

confidence: 99%

See 4 more Smart Citations

New aspects in the pathogenesis and management of subacute thyroiditis

Stasiak

Lewiński

2021

Rev Endocr Metab Disord

101

106

View full text Add to dashboard Cite

Subacute thyroiditis (SAT) is a thyroid inflammatory disease, whose pathogenesis and determinants of the clinical course were unclear for many decades. The last few years have brought many clinically significant new data on the epidemiology, pathogenesis and management of SAT. Several human leukocyte antigen (HLA) alleles were demonstrated not only to increase the risk of SAT, but also to correlate with SAT clinical course and determine the risk of recurrence. The world-wide epidemic of the coronavirus disease 19 (COVID-19) has provided new observations that the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) can be a potent SAT-triggering factor, and that the clinical course of SAT in patients affected by COVID-19 is different from a typical one. Additionally, many new trends in the clinical course are emerging. In the last years, painless course of SAT is more and more often described, constituting a special challenge in patients hospitalized due to COVID-19. Despite an excellent availability of diagnostic methods, several difficulties in SAT differential diagnosis can be currently encountered and the proper diagnosis and treatment is frequently delayed. False positive diagnoses of SAT in patients with malignancies of poor prognosis constitute a life-threatening problem. Taking into account all the new aspects of SAT pathogenesis and of its clinical course, the new – modified – SAT diagnosis criteria have been proposed.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Epidemiologymentioning

confidence: 99%

Section: Current Clinical Manifestation and Factors Modifying Clinical Coursementioning

confidence: 99%

Section: Current Clinical Manifestation and Factors Modifying Clinical Coursementioning

confidence: 99%

See 3 more Smart Citations

New aspects in the pathogenesis and management of subacute thyroiditis

Stasiak

Lewiński

2021

Rev Endocr Metab Disord

101

106

View full text Add to dashboard Cite

show abstract

SARS-CoV-2 and Subacute Thyroiditis: A Case Report and Literature Review

Salehi

Mohammadi

et al. 2022

Case Reports in Medicine

View full text Add to dashboard Cite

Introduction. Subacute thyroiditis (SAT) is an inflammatory disorder of the thyroid gland, usually triggered by a recent viral or bacterial infection of upper respiratory tracts. The disease is characterized by neck pain radiating to the ears and thyroid gland tenderness. In most cases, it is associated with a transient episode of hyperthyroidism, which is followed by euthyroidism. However, sometimes, it manifests itself with hypothyroidism. Case Presentation. The present report described a case of SAT who was a 55-year-old man presenting to an endocrine clinic with tachycardia, tremor, and neck pain radiating to the jaw and ears. His thyroid function test revealed thyrotoxicosis, and thyroid ultrasound findings were consistent with SAT. The patient reported a history of COVID-19 about 15 days before presentation, which was confirmed by a positive PCR test for SARS-CoV-2. Conclusions. It is of great importance for physicians to note that thyrotoxicosis in a patient with a recent history of COVID-19 can be due to SAT. Therefore, they should not begin antithyroid drugs without ordering proper investigations.

show abstract

Subacute thyroiditis: clinical significance of diffuse 18-fluorodeoxyglucose uptake. Case report

Огнерубов

Antipova²,

Palkina

2023

Consilium Medicum

View full text Add to dashboard Cite

Background. Subacute thyroiditis is a rare inflammatory thyroid disease presumably associated with viral infection, including COVID-19. It accounts for about 5% of all thyroid diseases. Materials and methods. A clinical case of de Quervain's subacute thyroiditis in a patient with diffuse hypermetabolic 18-fluorodeoxyglucose uptake by the thyroid gland is presented. Results. A 61-year-old patient with no history of thyroid disorders 3 weeks after COVID-19 experienced fever in the evenings (37.839.8C). He had moderate pain in the thyroid gland with radiation to the jaw, severe weakness, hand tremors, shivers, 12 kg weight loss, and sweating. These symptoms lasted for 3 weeks. Physical examination showed an enlarged thyroid gland, dense and extremely tender, especially its left lobe. Ultrasound showed an enlarged thyroid gland with a heterogeneous structure and large hypoechoic areas in both lobes up to 47 mm with fuzzy contour. Color Doppler imaging revealed reduced blood flow. Combined positron-emission and X-ray computed tomography with 18-fluorodeoxyglucose showed an increased diffuse uptake of the radiopharmaceutical in the thyroid gland and enlargement of its lobes, SUVmax 10.55. Blood thyroid-stimulating hormone is low, free triiodothyronine and thyroxine are high, and ferritin concentration is markedly increased, consistent with thyrotoxicosis. A fine-needle aspiration biopsy was performed. Cytology confirmed de Quervain's subacute thyroiditis. Glucocorticoids and nonsteroidal anti-inflammatory drugs were administered. Four weeks after the treatment, the clinical manifestations resolved. The patient was assessed in 6 months. Ultrasound showed a thyroid gland of regular size with smooth contours; color Doppler mapping revealed normal blood flow. Thyroid-stimulating hormone, triiodothyronine, and thyroxine were within reference ranges. Conclusion. The SARS-CoV-2 virus can be regarded as the cause of subacute thyroiditis. Combined positron-emission and X-ray computed tomography with 18-fluorodeoxyglucose showed diffuse intensive radiopharmaceutical uptake in the thyroid gland. Cytology is the basis for differential diagnostics. Glucocorticoids and nonsteroidal anti-inflammatory drugs are the first-choice agents.

show abstract

Subacute thyroiditis with airway compromise in a 5-year-old boy

Cited by 5 publications

References 16 publications

New aspects in the pathogenesis and management of subacute thyroiditis

New aspects in the pathogenesis and management of subacute thyroiditis

SARS-CoV-2 and Subacute Thyroiditis: A Case Report and Literature Review

Subacute thyroiditis: clinical significance of diffuse 18-fluorodeoxyglucose uptake. Case report

Contact Info

Product

Resources

About