Subacute sclerosing panencephalitis in only one member of a monozygotic twin pair

Lefèvre, Antônio B.; Canelas, Horacio M.; Grossmann, R; Salles-Gomes, Luís Florêncio de; Saldanha, P. H.

doi:10.1016/0022-510x(74)90176-2

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1979

1987

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Cited by 12 publications

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“…Among these 63 patients with SSPE was a case of monozygotic twins. Measles infection occurred simultaneously in both twins at the 1972, D'Onghia et al 1974, Yoshioka et al 1980, Cianchetti et al 1983) and only one report of concordant twins whose zygosity was unknown (Michalowicz et al 1985). These suggest that genetic factors are not strongly involved in pathogenesis of SSPE.…”

Section: Resultsmentioning

confidence: 99%

HLA and C4 in subacute sclerosing panencephalitis

et al. 1987

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The frequencies of HLA-A, B, C, DR and DO antigens were studied in 63 Japanese patients with subacute sclerosing panencephalitis (SSPE). The results could not confirm the statistical association between SSPE and HLA antigens. In addition, the allele frequencies of complement components C4, C2 and BF were determined in the 20 haplotypes with 10 unrelated SSPE patients. A significant association of C4A'QO with SSPE in Caucasians was not found in Japanese.

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Section: Resultsmentioning

confidence: 99%