Subacute Necrotizing Encephalopathy in Late Adolescence

Hardman, John; Allen, Liz; Baughman, Fred A.; Waterman, Donald F.

doi:10.1001/archneur.1968.00470350036003

Cited by 21 publications

(7 citation statements)

References 23 publications

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“…Adult and juvenile cases of this disease were also described (Hardman et al, 1968;Feigin and Goebel, 1969;Solheid et al, 1971;Martin, \917\Sipe, 1973), but are exceptional.…”

Section: Discussionmentioning

confidence: 90%

Subacute Necrotizing Encephalopathy (Leigh) in an Adult

Ulrich¹,

Fankhauser-Mauri²

1978

Eur Neurol

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The case of a 31-year-old man who died after a 4 month illness of adult subacute necrotizing encephalomyelopathy (Leigh) is reported. The disease presented with visual disturbances and the principal symptoms were ptosis, a conjugate ophthalmoparesis and a slight tremor of the hands. The case was misdiagnosed as probable multiple sclerosis. Neuropathology disclosed characteristic symmetrical necrotizing lesions, mainly localized in the brain stem. The similarity of the lesions with Wernicke’s disease is pointed out. Possible etiological and pathogenetic factors are discussed.

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“…Adult and juvenile cases of this disease were also described (Hardman et al, 1968;Feigin and Goebel, 1969;Solheid et al, 1971;Martin, \917\Sipe, 1973), but are exceptional.…”

Section: Discussionmentioning

confidence: 90%

Subacute Necrotizing Encephalopathy (Leigh) in an Adult

Ulrich¹,

Fankhauser-Mauri²

1978

Eur Neurol

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“…Pyramidenbahnzeichen und Demenz. eine Stoffwechselstörung mit autosomal rezessivem Erbgang [Leigh, 1951;Hardman et al, 1968;liorit, 1971]. Nach neueren Untersuchungen findet man bei einem gewissen Prozentsatz dieser Patienten einen Enzymhemmstoff, welcher die Bildung von Thiamintriphosphat aus Thiaminpyrophosphat be hindert [Piitcus et al, 1974 van Weerden, 1978].…”

Section: Methodik Und Kasuistikunclassified

Verlangsamte Sakkaden bei verschiedenen neurologischen Erkrankungen

Hamann¹

1979

Ophthalmologica

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“…Tab. 1 Ursachen einer internukleären Ophthalmoplegie (nach Bohan und Peter 1975, BoIler et al 1972, Brandt und BUchele 1983, Gonyea 1974, Cogan und Mount 1963, Cogan 1970, Dawson und Fischer 1977, Devereaux et al 1979, Eadie 1975, Fötzsch 1971, Cahill et al 1981, Greer und Schotland 1962, Hardman et al 1968, Leigh und Zee 1983, Le Witt 1981, MacDonald und Sher 1977, Patten und Pages 1984, Pillay et al 1984, Plum und Posner 1980, Rizzo und Corbett 1983, van Vliet 1976, Yee et al 1976…”

Section: Aktuelle Neurologieunclassified