Subacute atrophy of the liver has been described by several authors during the past few years. It is a condition which closely resembles acute yellow atrophy of the liver in its etiology and initial symptoms, but it differs from acute yellow atrophy in that the progress of the disease is less acute, the onset of the second or terminal stage is delayed or absent, and fatal termination does not occur for weeks, months or even years after the initial symptoms. The condition is very rare.McDonald and Milne1 collected the reports of the fifteen cases which had been reported previously to 1909, and added five new cases. Milne2 has since reported one more case, and Fordyce3 had added another. In a fairly complete review of the literature I have been unable to find any other reported cases, although Milne mentions having seen specimens of four cases which have not been reported. In view of the infrequency of the condition it would seem justifiable to report the following case:REPORT OF CASE Baby C. was an apparently normal, 8-pound baby, the first child of young and healthy parents. He was breast-fed for about two months, after which he was placed on a formula diet. He thrived and steadily increased in weight.When about 2 weeks old he became deeply jaundiced, although there was no gastro-intestinal disturbance and no other sign of illness. The stools were not acholic. The child continued to grow and was apparently healthy, although the deep jaundice persisted. Dr. R. Langley Porter was called in consultation on account of the persisting jaundice when the child was about 3 months of age. He found a well-grown, well-nourished child which showed no abnormal¬ ity except a marked jaundice, a palpable spleen and a slightly enlarged liver. The stools were not acholic and the child appeared healthy and happy. The blood of the child and of the parents gave a negative Wassermann reaction. Dr. Porter believed that the case was one of persistent icterus neonatorum. The child was seen only occasionally by the attending physician during the following weeks, but regular reports were received from the parents, who said that he was steadily gaining in weight although the jaundice persisted. Two months after Dr. Porter saw him, the child was seized with extreme respir-