2021
DOI: 10.1136/bcr-2021-242443
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Subacute effusive-constrictive pericarditis in a patient with COVID-19

Abstract: We report the case of a previously healthy young woman, who developed a severe form of COVID-19 with massive pneumonia and acute pericarditis in whom constrictive physiology developed rapidly. To our knowledge, this represents the second reported case of SARS-CoV-2 constrictive pericarditis, a rare, but severe cardiac complication.

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Cited by 14 publications
(10 citation statements)
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References 21 publications
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“…Though an early case of CP with COVID-19 has been described in medical literature [ 82 ], there is uncertainty about the risk of progression of COVID pericarditis into CP as the natural history of CP usually extends over years to even decades. There are reports of transient or effusive-constrictive pericarditis with COVID-19 infection or vaccination [ 83 , 84 ]; however, the real impact of this infection on CP is unknown.…”
Section: Covid-19 and Constrictive Pericarditismentioning
confidence: 99%
“…Though an early case of CP with COVID-19 has been described in medical literature [ 82 ], there is uncertainty about the risk of progression of COVID pericarditis into CP as the natural history of CP usually extends over years to even decades. There are reports of transient or effusive-constrictive pericarditis with COVID-19 infection or vaccination [ 83 , 84 ]; however, the real impact of this infection on CP is unknown.…”
Section: Covid-19 and Constrictive Pericarditismentioning
confidence: 99%
“…Although coronavirus disease 2019 (COVID-19) has been extensively studied, the pathogenesis of the interplay between COVID-19 and cardiovascular disease remains largely unclear. During the pandemic, several cases of acute pericarditis, pericardial effusion, and cardiac tamponade allegedly related to COVID-19 have been described [2], but only three cases of constrictive or effusive-constrictive pericarditis in SARS-CoV-2 infection have already been reported [7][8][9]. Specifically, in two cases the patients developed constrictive-effusive pericarditis during the acute phase of COVID-19, and subsequently died of severe respiratory failure [8,9].…”
Section: Discussionmentioning
confidence: 99%
“…During the pandemic, several cases of acute pericarditis, pericardial effusion, and cardiac tamponade allegedly related to COVID-19 have been described [2], but only three cases of constrictive or effusive-constrictive pericarditis in SARS-CoV-2 infection have already been reported [7][8][9]. Specifically, in two cases the patients developed constrictive-effusive pericarditis during the acute phase of COVID-19, and subsequently died of severe respiratory failure [8,9]. In the third case, pericardial effusion with cardiac tamponade was observed in a patient with several in-hospital complications, four months after COVID-19; the patient ultimately needed a pericardiocentesis [7].…”
Section: Discussionmentioning
confidence: 99%
“…2D imaging has an excellent ability to detect effusion, enlarged atrial size, interventricular septum bounce, and a dilated IVC, which are sensitive and specific signs for the initial diagnosis of ECP. The echo-Doppler findings are diagnostically helpful, and it has been proposed that the presence of constrictive pericarditis echocardiographic Doppler features after pericardiocentesis would help clarify the diagnosis of ECP[ 8 , 9 ]. The key characteristic performance features of ECP include “annulus reversus,” restrictive mitral inflow (E/A > 2), greater than 25% respiratory variation in the peak mitral inflow velocity (E)[ 10 ].…”
Section: Discussionmentioning
confidence: 99%