Abstract:Background Subacute combined degeneration (SCD) is a neurodegenerative disease caused by vitamin B 12 deficiency. The lesions mainly involve the posterior cord, lateral cord, and peripheral nerves. Occasionally, the lesions also involve brain white matter and optic nerves in severe cases. Reports of drug-induced impaired absorption and metabolism of vitamin B 12 resulting in SCD are scarce. Introduction A patient developed SCD after long-term use of tripterygium glycoside tablets in the treatment of glomerulon… Show more
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