<sub>Probiotics and Other Bioactive Compounds with Proven Effect against Obesity and Hypertension: Food Design Opportunities from Lulo Fruit (<i>Solanum quitoense</i>)</sub>

Betoret, Noelia; Hinestroza, Leidy Indira; Seguí, Lucía; Barrera, Cristina

doi:10.5772/intechopen.85482

Cited by 3 publications

(3 citation statements)

References 84 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The biopharmaceutical effect depends on their chemical structure and their individual bioassimilation ability. A significant limiting factor is the lack of standardization, and the administration period is one of the two essential causes of reducing the efficacy in vivo [64].…”

Section: Predictive Microbiota Responsementioning

confidence: 99%

Correlations between Microbiota Bioactivity and Bioavailability of Functional Compounds: A Mini-Review

Vamanu

Gatea

2020

Biomedicines

View full text Add to dashboard Cite

Numerous studies have demonstrated the role of the microbiota in supporting the physiological functions, owing to its metabolomic component. The presence of biocomponents generally leads to the correction of the microbial pattern correlated with the reduction of oxidative pressure. This study aims to present the main processes that correlate the bioavailability and bioactivity of some functional components through the action of the human microbiota. The use of probiotics and prebiotics is an innovative manner involving alternatives that increase the bioavailability of certain natural or metabolic components has been proposed. Probiotic strains (Saccharomyces cerevisiae or Lactobacillus (L.) plantarum) may represent an intermediary for increasing the antioxidant bioactivity, and they may be administered in the form of a biomass enriched with functional compounds, such as phenolic acids. The limiting effect of gastrointestinal transit is, in several cases, the key to the biopharmaceutical value of new products (or supplements). The identification of newer ways of formulating supplements also involves the compatibility of different types of products, the testing of bioaccessibility, and the elimination of biotransformations.

show abstract

Section: Predictive Microbiota Responsementioning

confidence: 99%

Correlations between Microbiota Bioactivity and Bioavailability of Functional Compounds: A Mini-Review

Vamanu

Gatea

2020

Biomedicines

View full text Add to dashboard Cite

show abstract

“…In recent years, probiotics have been used in developing functional foods or dietary supplements (Kerry et al, 2018;Betoret et al, 2019). Probiotics are defined as "live microorganisms which when administered in adequate amounts confer one or more health benefit on the host" (Araya et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

Screening for Potential Novel Probiotics With Dipeptidyl Peptidase IV-Inhibiting Activity for Type 2 Diabetes Attenuation in vitro and in vivo

Yan

Yue

et al. 2020

Front. Microbiol.

View full text Add to dashboard Cite

Diabetes has become the second most severe disease to human health. Probiotics are important for maintaining gastrointestinal homeostasis and energy balance and have been demonstrated to play a positive role in the prevention and treatment of metabolic syndromes, such as obesity, inflammation, dyslipidemia, and hyperglycemia. The objective of this study was to screen potential antidiabetic strains in vitro and evaluate its effects in vivo. For the in vitro section, dipeptidyl peptidase IV (DPP-IV) inhibitory and antioxidant activities of 14 candidate Lactobacillus spp. strains were tested. Then hydrophobicity and acid and bile salt tolerance assays were determined. The most promising in vitro strain was further evaluated for its antidiabetic properties in vivo using type 2 diabetes mice induced by high-fat diet and intraperitoneal injection of streptozotocin (STZ). The reference strain for this study was Lactobacillus rhamnosus GG. Results showed that cell-free excretory supernatants and cell-free extracts of Lactobacillus acidophilus KLDS1.0901 had better DPP-IV inhibitory activity, antioxidative activities, and biological characteristics than other strains. At the end of the treatment, we found that L. acidophilus KLDS1.0901 administration decreased the levels of fasting blood glucose (FBG), glycosylated hemoglobin, insulin in serum and AUC glucose , and increased the level of glucagon-like peptide 1 in serum compared with diabetic mice (p < 0.05). Moreover, L. acidophilus KLDS1.0901 supplementation increased the activities of superoxide dismutase, glutathione peroxidase, the level of glutathione, and reduced the level of malondialdehyde in serum. These results indicated that L. acidophilus KLDS1.0901 could be used as a potential antidiabetic strain; its application as food supplement and drug ingredient is thus recommended.

show abstract

“…This bitter taste could be induced by the thermal reactions of food processing , 1985). In that sense, the spermidine components found in the lulo fruit after processing could help people with high blood pressure problems (Betoret et al, 2020).…”

Section: Other Compoundsmentioning

confidence: 99%

Nutritional and Bioactive Properties of Solanum Quitoense Lam: Native Fruit From the South American Andes

Obregon,

López,

Angeles

2023

J microb biotech food sci

View full text Add to dashboard Cite

The increasing interest in tropical fruits has been observed worldwide, driven by their desirable sensory and nutritional characteristics. Lulo (Solanum quitoense L.), an exotic and native South American fruit, is predominantly used in beverage production and commercially marketed in Colombia and Ecuador. However, the perishable nature presents challenges for their commercialization to market. This has prompted food researchers to be interested in developing new Lulo-based products, that can have an agro-industrial impact in the countries of origin. Lately, a growing number of studies have aimed to uncover the nutritional and bioactive properties of Lulo. These studies have revealed that the fruit is rich in vitamin C, chlorogenic acids, phenolic compounds, and bioactive amines, making it an attractive raw material for the agri-food and pharmaceutical industries. This review summarizes the current understanding of the properties of Solanum quitoense L., including its physicochemical, nutritional, and bioactive properties. The fruit's high concentration of beneficial compounds has increased interest from industries and presents new opportunities for economic growth in the countries where it is grown. The growing demand for natural products underscores the need for further research on Lulo's potential applications and benefits, which could result in the development of new and economically viable products.

show abstract

_{Probiotics and Other Bioactive Compounds with Proven Effect against Obesity and Hypertension: Food Design Opportunities from Lulo Fruit (Solanum quitoense)}

Cited by 3 publications

References 84 publications

Correlations between Microbiota Bioactivity and Bioavailability of Functional Compounds: A Mini-Review

Correlations between Microbiota Bioactivity and Bioavailability of Functional Compounds: A Mini-Review

Screening for Potential Novel Probiotics With Dipeptidyl Peptidase IV-Inhibiting Activity for Type 2 Diabetes Attenuation in vitro and in vivo

Nutritional and Bioactive Properties of Solanum Quitoense Lam: Native Fruit From the South American Andes

Contact Info

Product

Resources

About