Abstract:Improved preservation strategies for the storage of graft collected after circulatory death could increase the number of kidneys available and improve patient survival. Warm (22 and 37°C) ex-vivo perfusion has emerged as a feasible strategy for organ recovery, but the underlying mechanism remains elusive. Using phosphorus magnetic resonance spectroscopic imaging (31P-MRSI) and histological scoring, we evaluated kidney viability and adenosine triphosphate (ATP) production during sub-normothermic ex-vivo… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.