Sub‐chronic consumption of a phenolic‐rich avocado paste extract induces GLP‐1‐, leptin‐, and adiponectin‐mediated satiety in Wistar rats

Corella-Salazar, Diana A.; Domínguez-Ávila, J. Abraham; Montiel‐Herrera, Marcelino; Astiazarán-García, Humberto; Salazar‐López, Norma Julieta; Serafín-García, Mitsuky Soraya; Olivas, Guadalupe I.; Molina-Corral, Francisco Javier; González‐Aguilar, Gustavo A.

doi:10.1111/jfbc.13957

Cited by 4 publications

(1 citation statement)

References 54 publications

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“…The regulation of the beginning and cessation of food intake, as well as the interval between meals, is mediated by a complex and structured control mechanism that integrates peripheral signals in the central nervous system into hunger/satiety, actions related to food intake and systemic energy metabolism [ 7 ]. In this regard, previous studies have reported that certain dietary compounds are capable of modulating some hunger–satiety mediators, which could directly impact adipose deposition and, therefore, body weight [ 5 , 8 ].…”

Section: Introductionmentioning

confidence: 99%

Could Naringenin Participate as a Regulator of Obesity and Satiety?

et al. 2023

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Obesity is a serious health problem worldwide, since it is associated with multiple metabolic disorders and complications such as cardiovascular disease, type 2 diabetes, fatty liver disease and overall metabolic dysfunction. Dysregulation of the hunger–satiety pathway, which includes alterations of central and peripheral signaling, explains some forms of obesity by favoring hyperphagia and weight gain. The present work comprehensively summarizes the mechanisms by which naringenin (NAR), a predominant flavanone in citrus fruits, could modulate the main pathways associated with the development of obesity and some of its comorbidities, such as oxidative stress (OS), inflammation, insulin resistance (IR) and dyslipidemia, as well as the role of NAR in modulating the secretion of enterohormones of the satiety pathway and its possible antiobesogenic effect. The results of multiple in vitro and in vivo studies have shown that NAR has various potentially modulatory biological effects against obesity by countering IR, inflammation, OS, macrophage infiltration, dyslipidemia, hepatic steatosis, and adipose deposition. Likewise, NAR is capable of modulating peptides or peripheral hormones directly associated with the hunger–satiety pathway, such as ghrelin, cholecystokinin, insulin, adiponectin and leptin. The evidence supports the use of NAR as a promising alternative to prevent overweight and obesity.

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Section: Introductionmentioning

confidence: 99%

Could Naringenin Participate as a Regulator of Obesity and Satiety?

et al. 2023

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Avocado Paste Phenolics Mitigate a High-Fat Diet-Induced Plasma HDL Decrease in Male Wistar Rats, by Altering the mRNA Expression of Hepatic SCARB1

Domínguez-Avila,

Salazar-López,

Montiel-Herrera

et al. 2023

Cell Biochem Biophys

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Supercritical Technology as an Efficient Alternative to Cold Pressing for Avocado Oil: A Comparative Approach

Pinheiro Pantoja,

Melo Aires,

Ferreira

et al. 2024

Foods

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Avocado oil is rich in nutrients beneficial to human health, such as monounsaturated fatty acids, phenolic compounds, tocopherol, and carotenoids, with numerous possibilities for application in industry. This review explores, through a comparative approach, the effectiveness of the supercritical oil extraction process as an alternative to the conventional cold-pressing method, evaluating the differences in the extraction process steps through the effect of temperature and operating pressure on bioactive quality and oil yield. The results reveal that supercritical avocado oil has a yield like that of mechanical cold pressing and superior functional and bioactive quality, especially in relation to α-tocopherol and carotenoids. For better use and efficiency of the supercritical technology, the maturation stage, moisture content, fruit variety, and collection period stand out as essential factors to be observed during pre-treatment, as they directly impact oil yield and nutrient concentration. In addition, the use of supercritical technology enables the full use of the fruit, significantly reducing waste, and adds value to the agro-industrial residues of the process. It produces an edible oil free of impurities, microorganisms, and organic solvents. It is a green, environmentally friendly technology with long-term environmental and economic advantages and an interesting alternative in the avocado market.

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Sub‐chronic consumption of a phenolic‐rich avocado paste extract induces GLP‐1‐, leptin‐, and adiponectin‐mediated satiety in Wistar rats

Cited by 4 publications

References 54 publications

Could Naringenin Participate as a Regulator of Obesity and Satiety?

Could Naringenin Participate as a Regulator of Obesity and Satiety?

Avocado Paste Phenolics Mitigate a High-Fat Diet-Induced Plasma HDL Decrease in Male Wistar Rats, by Altering the mRNA Expression of Hepatic SCARB1

Supercritical Technology as an Efficient Alternative to Cold Pressing for Avocado Oil: A Comparative Approach

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