The emergence of the Industry 4.0 revolution to upgrade the Internet of Things (IoT) standards provides the prominence outcomes for the future wireless communication systems called 5G. The development of 5G green communication systems suffers from the various challenges to fulfill the requirement of higher user capacity, network speed, minimum cost, and reduced resource consumption. The use of 5G standards for Industry 4.0 applications will increase data rate performance and connected device's reliability. Since the arrival of novel Covid-19 disease, there is a higher demand for smart healthcare systems worldwide. However, designing the 5G communication systems has the research challenges like optimum resource utilization, mobility management, cost-efficiency, interference management, spectral efficiency, etc. The rapid development of Artificial Intelligence (AI) across the different formats brings performance enhancement compared to conventional techniques. Therefore, introducing the AI into 5G standards will optimize the performances further considering the various end-user applications. We first present the survey of the terms like 5G standard, Industry 4.0, and some recent works for future wireless communications. The purpose is to explore the current research problems using the 5G technology. We further propose the novel architecture for smart healthcare systems using the 5G and Industry 4.0 standards. We design and implement that proposed model using the Network Simulator (NS2) to investigate the current 5G methods. The simulation results show that current 5G methods for resource management and interference management suffer from the challenges like performance trade-offs.
