“…4 The diagnosis and treatment of UC are both complex and expensive. 5,6 The traditional drugs for the treatment of UC are aminosalicylic acid, glucocorticoid and immunosuppressant. Unsatisfactory clinical efficacy, poor tolerance, easy to relapse after withdrawal, and many adverse reactions limit their use.…”
The therapeutic effect of indirubin on dextran sulfate sodium-induced colitis in mice and 3D cultured biopsies from patients was further enhanced by the nano-carrier system, making it a highly promising medical candidate for ulcerative colitis.
“…4 The diagnosis and treatment of UC are both complex and expensive. 5,6 The traditional drugs for the treatment of UC are aminosalicylic acid, glucocorticoid and immunosuppressant. Unsatisfactory clinical efficacy, poor tolerance, easy to relapse after withdrawal, and many adverse reactions limit their use.…”
The therapeutic effect of indirubin on dextran sulfate sodium-induced colitis in mice and 3D cultured biopsies from patients was further enhanced by the nano-carrier system, making it a highly promising medical candidate for ulcerative colitis.
“…1 These complex interactions control inammatory responses, and dysregulation of these mechanisms and/or introduction of microorganisms that produce compounds that stimulate inammation can lead to disease. 2 Incidence of inammatory bowel diseases, such as Crohn's disease, continues to increase. 3 One contributing cause to these diseases is the makeup of the microbiome.…”
The roles played by the gut microbiome in human health are increasingly recognized, and the prevalence of specific microorganisms has been correlated with different diseases.
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