Su1170 Second-Line Rescue Therapy With Levofloxacin After Failure of Treatment to Eradicate Helicobacter pylori Infection: Time Trends in a Spanish Multicenter Study of 1,400 Patients

Standard triple versus levofloxacin based regimen for eradication ofHelicobacter pylori

“…The emergence of resistance of the organism to clarithromycin has urged researchers to look for alternatives to the STT. The sequential therapy and levofloxacin based regimens are two of the newly recommended combinations [18][19][20][21][22] . Levofloxacin based regimens were used as rescue regimens in case of failure with standard regimen [23] .…”

Letter: bismuth, levofloxacin, amoxicillin, PPI quadruple therapy is not an effective first or second‐line regimen in the presence of levofloxacin resistance – authors' reply

“…Indeed, this novel second-line quadruple therapy has achieved the best eradication rates for second-line therapy in our experience with levofloxacin-containing therapies (Figure 1). 4,5 Cure rates in our study with this empiric quadruple regimen (≥90%) can be considered good (i.e. effective cure rates) for an H. pylori treatment, following the recommendations of Drs Graham and Lu in a previous study.…”

Efficacy of Two Levofloxacin‐Containing Second‐Line Therapies for Helicobacter pylori: A Pilot Study

“…We found similar eradication rates according to gender in two levofloxacin-containing therapy regimens. In a multicenter study [36], recently published, it is found that there was no difference in eradication rates by gender.…”