Abstract:Purpose: To develop a simple kinetic model for tumor survival curves which is able to describe their behavior for high and low LET clinical applications and at the same time can provide a relation to the mechanisms for DNA damage and repair. Method and Materials: Analytical and numerical solution of a nonlinear set of equations
urn:x-wiley:00942405:media:mp1994:mp1994-math-0001 where N is the number of clonogenic cells with undamaged DNA, NR is the number of cells with reversible DNA damage and NNR is the numb… Show more
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