Abstract:Purpose: Tumor metabolic activities obtained from PET studies may facilitate targeted dose delivery to improve local tumor control. We perform feasibility tests on TCP‐driven PET‐image‐guided dose escalation in high‐ dose‐rate‐brachytherapy(HDR). Quality and robustness of plans, TCP, and potential outcome significance are evaluated. Methods: CT and 18F‐ fluorodeoxyglucosebased‐PET images are obtained for cervical cancer patients. Planning‐target‐volumes(PTV) and critical structures are delineated. Enhanced PET… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.