“…Fractal methods are widely used techniques in medical physiology and biophysics (Lopes & Betrouni, 2009). Fractal and gray-level co-occurrence matrix (GLCM) analyses are very common in digital image processing, and are often used in radiology for analyzing different types of clinical and biological problems such as various tissue and tumor research (Assefa et al, 2010;Chan et al, 2010;Huber et al, 2011;Jambawalikar et al, 2011;Kao et al, 2011;Liao et al, 2011;Ranjanomennahary et al, 2011;Waugh et al, 2011). They are very sensitive and efficient in detecting subtle changes in ultrastructure of various cellular components that are otherwise undetectable (Pantic et al, 2012a(Pantic et al, , 2012b(Pantic et al, , 2015.…”