Stuttering Priapism: Insights into Pathogenesis and Management

Morrison, Belinda; Burnett, Arthur L.

doi:10.1007/s11934-012-0258-9

Cited by 41 publications

(59 citation statements)

References 62 publications

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“…[55][56][57][58][59][60][61][62] Additionally, they are associated with significant side effects including decreased libido, gynecomastia, delayed growth/ development due to premature epiphyseal plate closure, and could mask prostate-specific antigen elevations. 63,64 They are therefore, contraindicated in boys who have not completed sexual maturation and men wishing to conceive. 2 Conventional antiandrogenic therapies may represent a nonspecific approach for priapism management as they interfere with erectile tissue structure and function.…”

Section: -53mentioning

confidence: 99%

How I treat priapism

Anele

Resar

et al. 2015

Blood

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Priapism is a disorder of persistent penile erection unrelated to sexual interest or desire. This pathologic condition, specifically the ischemic variant, is often associated with devastating complications, notably erectile dysfunction. Because priapism demonstrates high prevalence in patients with hematologic disorders, most commonly sickle cell disease (SCD), there is significant concern for its sequelae in this affected population. Thus, timely diagnosis and management are critical for the prevention or at least reduction of cavernosal tissue ischemia and potential damage consequent to each episode. Current guidelines and management strategies focus primarily on reactive treatments. However, an increasing understanding of the molecular pathophysiology of SCD-associated priapism has led to the identification of new potential therapeutic targets. Future agents are being developed and explored for use in the prevention of priapism.

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Section: -53mentioning

confidence: 99%

How I treat priapism

Anele

Resar

et al. 2015

Blood

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“…Priapism is an abnormal prolonged and persistent penile erection lasting for more than 4 h that is unrelated to sexual desire, stimulation or activity [1][2][3][4][5] . Priapism is categorized into three types: low-flow (ischemic, veno-occlusive), high-flow (non-ischemic, arterial), and stuttering (recurrent or intermittent ischemic) 5 .…”

Section: Introductionmentioning

confidence: 99%

Case Report: Successful treatment of refractory high-flow priapism in a patient with sickle cell disease by selective trans-catheter embolization using an autologous blood clot: A case report

2018

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Priapism is an abnormal prolonged and persistent penile erection lasting more than 4 h, unrelated to sexual desire, stimulation or activity. The three types of priapism are low-flow, high-flow and stuttering. Patients with sickle cell disease (SCD) have increased risk of low-flow and stuttering priapism, but high-flow priapism is relatively uncommon in SCD. We report a case of non-traumatic refractory high-flow priapism evolving from a stuttering low-flow priapism in a patient with SCD. The patient was successfully treated by super-selective transcatheter embolization of the penile arteries with an autologous blood clot. It is proposed that the super-selective transcatheter embolization of unilateral or bilateral penile arteries with autologous blood clot is a relatively safe and effective non-surgical treatment option for high-flow priapism, even in patients with SCD, and has a low probability of developing erectile dysfunction.

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“…The cause can also be idiopathic and rarely due to a neurological disorder. Interventions for this type of recurrent problem include aggressive blockade of testosterone with ketoconazole (which requires supplementation of corticosteroids to prevent adrenal insufficiency), anti-androgens and luteinizing hormone-releasing hormone (LHRH) agonists, low dose of phosphodiesterase type 5 (PDE5) inhibitors and self injections of sympathomimetics [4].…”

Section: Introductionmentioning

confidence: 99%

Chlorpromazine induced priapism from a single dose: an unusual complication of antipsychotic agent

Ahmed¹,

Abdel‐latif²

2017

Russ Open Med J

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Priapism is considered as an unusual andrological emergency that requires urgent intervention. It is defined as prolonged penile erection (usually painful) for more than 4 hours not related to sexual excitation or stimulation. Several causes have been attributed to cause such condition including the use of psychotropic drugs as chlorpromazine. Only few case reports in literature have recorded priapism as a complication of administration of chlorpromazine, however most of them were due to overdose or prolonged administration for prolonged period or as an interaction with other drugs. Here, in this case report is about a 23 years old male presented to the emergency department with neglected priapism after administration of a single dose of chlorpromazine.

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Stuttering Priapism: Insights into Pathogenesis and Management

Cited by 41 publications

References 62 publications

How I treat priapism

How I treat priapism

Case Report: Successful treatment of refractory high-flow priapism in a patient with sickle cell disease by selective trans-catheter embolization using an autologous blood clot: A case report

Chlorpromazine induced priapism from a single dose: an unusual complication of antipsychotic agent

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