Studying the role of BCL2 and MYC in the pathogenesis of diffuse large B cell lymphoma
Javier Melchor
Abstract:Approximately 30% of patients with diffuse large B-cell lymphoma (DLBCL) co-express BCL2 and MYC, known as double-expressor lymphomas (DEL). These lymphomas associate with poorer prognosis and response to standard-of-care R-CHOP, and a preferred therapeutic alternative has not been identified yet.
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