Studying the photothermal activation of polydopamine-shelled, phase-change emulsion droplets into microbubbles using small- and ultra-small-angle neutron scattering

Vidallon, Mark Louis P.; King, Joshua P.; Giles, Luke W.; Crawford, Simon A.; Baldwin, Chris; Premilovac, Dino; Mian Teo, Boon; Bishop, Alexis I.; de Campo, Liliana; Tabor, Rico F.

doi:10.1016/j.jcis.2024.01.004

Journal of Colloid and Interface Science

2024

DOI: 10.1016/j.jcis.2024.01.004

|View full text |Cite

Studying the photothermal activation of polydopamine-shelled, phase-change emulsion droplets into microbubbles using small- and ultra-small-angle neutron scattering

Mark Louis P. Vidallon,

Joshua P. King,

Luke W. Giles

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Revealing the Structural Intricacies of Biomembrane‐Interfaced Emulsions with Small‐ and Ultra‐Small‐Angle Neutron Scattering

Vidallon,

Williams,

Moon

et al. 2024

Small Methods

View full text Add to dashboard Cite

Utilizing cell membranes from diverse cell types for biointerfacing has demonstrated significant advantages in enhancing colloidal stability and incorporating biological properties, tailored specifically for various biomedical applications. However, the structures of these materials, particularly emulsions interfaced with red blood cell (RBC) or platelet (PLT) membranes, remain an underexplored area. This study systematically employs small‐ and ultra‐small‐angle neutron scattering (SANS and USANS) with contrast variation to investigate the structure of emulsions containing perfluorohexane within RBC (RBC/PFH) and PLT membranes (PLT/PFH). The findings reveal that the scattering length density of RBC and PLT membranes is 1.5 × 10−6 Å−2, similar to 30% (w/w) deuterium oxide. Using this solvent as a cell membrane‐matching medium, estimated droplet diameters are 770 nm (RBC/PFH) and 1.5 µm (PLT/PFH), based on polydispersed sphere model fitting. Intriguingly, calculated patterns and invariant analysis reveal native droplet architectures featuring entirely liquid PFH cores, differing significantly from the observed bubble–droplet core system in electron microscopy. This highlights the advantage of SANS and USANS in differentiating genuine colloidal structures in complex dispersions. In summary, this work underscores the pivotal role of SANS and USANS in characterizing biointerfaced colloids and in uncovering novel colloidal structures with significant potential for biomedical applications and clinical translation.

show abstract

Revealing the Structural Intricacies of Biomembrane‐Interfaced Emulsions with Small‐ and Ultra‐Small‐Angle Neutron Scattering

Vidallon,

Williams,

Moon

et al. 2024

Small Methods

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Studying the photothermal activation of polydopamine-shelled, phase-change emulsion droplets into microbubbles using small- and ultra-small-angle neutron scattering

Cited by 1 publication

References 32 publications

Revealing the Structural Intricacies of Biomembrane‐Interfaced Emulsions with Small‐ and Ultra‐Small‐Angle Neutron Scattering

Revealing the Structural Intricacies of Biomembrane‐Interfaced Emulsions with Small‐ and Ultra‐Small‐Angle Neutron Scattering

Contact Info

Product

Resources

About