Studying the effect of PDA@CeO₂ nanoparticles with antioxidant activity on the mechanical properties of cells

Abstract

Studying the influence of nanomaterials on the microstructure and mechanical properties of cells is essential to guide the biological application of nanomaterials. In this article, the effect of the first...

Polydopamine-Pd nanozymes as potent ROS scavengers in combination with near-infrared irradiation for osteoarthritis treatment

“…developed a complex nanozyme PDA@CeO 2 to maintain normal cell morphology by scavenging ROS. 28 Xiaochun Hu et al. established a nanozyme by combining Pt nanozymes and PDA that can overcome tumor hypoxia by decomposing H 2 O 2 .…”

Aptamer conjugated polydopamine-coated gold nanoparticles as a dual-action nanoplatform targeting β-amyloid peptide for Alzheimer's disease therapy

“…Neurodegeneration caused by Ab 1-40 was considered to begin with damaged cell membranes, and the damage can be evaluated by morphology and mechanical properties. 49,50 The effect of Au@PDA-Apt NPs on the cell morphology and Young's modulus in Ab 1-40 -induced PC12 cells were examined using AFM PeakForce QNM technology. The typical force-distance curves were collected on PC12 cells, which were used to extract the Young's modulus of cells (Fig.…”

Revealing the Effect of Photothermal Therapy on Human Breast Cancer Cells: A Combined Study from Mechanical Properties to Membrane HSP70

“…Atomic force microscopy (AFM) can perform high-resolution imaging and mechanical detection of living cells under physiological conditions . Especially, the force-distance curve-based AFM (FD-based AFM), with pico-level force sensitivity, is a helpful tool for obtaining multiparametric imaging of complex biological samples.…”

“…20,21 Atomic force microscopy (AFM) can perform highresolution imaging and mechanical detection of living cells under physiological conditions. 22 Especially, the force-distance curve-based AFM (FD-based AFM), with pico-level force sensitivity, is a helpful tool for obtaining multiparametric imaging of complex biological samples. It has been used to study the distribution of toll-like receptor-4 on living cells, 23 the distribution of vitronectin receptors on living MC3T3-E1 cells, 24 and the binding properties of viruses to living cells 25 with very promising applications.…”