Studying the Bioactive Components and Phytochemicals of the Methanol Extract of Rhanterium epapposum Oliv.

El-Ashmawy, Ibrahim M.; Aljohani, Abdullah S. M.; Soliman, Amal S.

doi:10.1007/s12010-023-04574-y

Cited by 3 publications

(1 citation statement)

References 16 publications

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“…In vitro-derived calluses, leaves, and roots of adventitious origin, harvested from best growth media (callus from 4.0 mg/L BAP+ 3.5 mg/L Kn; shoot leaf from 4.5 mg/L BAP+ 4.0 mg/L Kn; and root from 1.0 mg/L IAA) were dried in sterilized condition and finely ground. The powdered samples of the above-mentioned tissues were soaked in 100% methanol (1.0 gm in 5.0 mL) for 12 h [22]. Syringe filter of pore size 0.22 µm was used to filter the extracts.…”

Section: Preparation Of Plant Methanolic Extract For Gc-ms Analysis A...mentioning

confidence: 99%

In Vitro Propagation and Phytochemical Composition of Centratherum punctatum Cass—A Medicinal Plant

Talan,

Mujib,

Ejaz

et al. 2023

Horticulturae

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An effective and reproducible micropropagation protocol was developed for Centratherum punctatum Cass. Successful in vitro initiation of callus and subsequent plant regeneration were obtained on nodal explants cultured on MS medium supplemented with plant growth regulators (PGRs). The maximum frequency of callus formation (98.3%) was noted on MS containing 4.0 mg/L 6-Benzylaminopurine (BAP) and 3.5 mg/L Kinetin with a maximum callus weight of 2.02 g. The best shoot induction frequency (100%) with an average of 30.2 shoots per explant was achieved when 4.5 mg/L BAP and 4.0 mg/L Kinetin were added to the MS. The same PGR combination resulted in the best callus-mediated shoot formation (8.3 shoots/callus mass). The highest rhizogenic response (95.3%) with an average 26.1 roots per shoot and root length of 6.2 cm was obtained with 1.0 mg/L Indole-3-acetic acid (IAA)-supplemented MS medium. The gas chromatography–mass spectrometry (GC-MS) technique was applied in the present study to analyze the methanolic extracts of the leaf, callus, and root of regenerated C. punctatum shoots to detect the different phytochemical constituents. The leaf extract of the regenerated C. punctatum showed 37 phytocompounds; some important bioactive compounds were the Phytol,1,6-Octadien 3,5-Dimethyl-Cis, 4,8-Dimethylnona-3,8-dien-2-one, 2,6-Octadiene, Stigmasterol, Chondrillasterol, Lanosteryl acetate, etc. In the callus, the extract had a total of 57 phytocompounds; among them, the Stigmasterol, Guanosine, and Tri-decanoic acid were the major ones. In the root extract, the GC-MS revealed a low number of 23 phytocompounds, the important compounds of which were Stigmasterol, Trimethylsilyl (TMS) derivative, Chrysantenyl 2-methuylbutanoate, 4-tert-Butoxybutan-1-ol, etc. The order in terms of numbers of phytocompounds present in tissue sources are callus > leaf > root.

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Section: Preparation Of Plant Methanolic Extract For Gc-ms Analysis A...mentioning

confidence: 99%

In Vitro Propagation and Phytochemical Composition of Centratherum punctatum Cass—A Medicinal Plant

Talan,

Mujib,

Ejaz

et al. 2023

Horticulturae

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Polyphenols of the Inuleae-Inulinae and Their Biological Activities: A Review

Malarz,

Michalska,

Stojakowska

2024

Molecules

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Polyphenols are ubiquitous plant metabolites that demonstrate biological activities essential to plant–environment interactions. They are of interest to plant food consumers, as well as to the food, pharmaceutical and cosmetic industry. The class of the plant metabolites comprises both widespread (chlorogenic acids, luteolin, quercetin) and unique compounds of diverse chemical structures but of the common biosynthetic origin. Polyphenols next to sesquiterpenoids are regarded as the major class of the Inuleae-Inulinae metabolites responsible for the pharmacological activity of medicinal plants from the subtribe (Blumea spp., Dittrichia spp., Inula spp., Pulicaria spp. and others). Recent decades have brought a rapid development of molecular and analytical techniques which resulted in better understanding of the taxonomic relationships within the Inuleae tribe and in a plethora of data concerning the chemical constituents of the Inuleae-Inulinae. The current taxonomical classification has introduced changes in the well-established botanical names and rearranged the genera based on molecular plant genetic studies. The newly created chemical data together with the earlier phytochemical studies may provide some complementary information on biochemical relationships within the subtribe. Moreover, they may at least partly explain pharmacological activities of the plant preparations traditionally used in therapy. The current review aimed to systematize the knowledge on the polyphenols of the Inulae-Inulinae.

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Recent Progress in Terrestrial Biota Derived Antibacterial Agents for Medical Applications

Vladkova,

Smani,

Martinov

et al. 2024

Molecules

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Conventional antibiotic and multidrug treatments are becoming less and less effective and the discovery of new effective and safe antibacterial agents is becoming a global priority. Returning to a natural antibacterial product is a relatively new current trend. Terrestrial biota is a rich source of biologically active substances whose antibacterial potential has not been fully utilized. The aim of this review is to present the current state-of-the-art terrestrial biota-derived antibacterial agents inspired by natural treatments. It summarizes the most important sources and newly identified or modified antibacterial agents and treatments from the last five years. It focuses on the significance of plant- animal- and bacteria-derived biologically active agents as powerful alternatives to antibiotics, as well as the advantages of utilizing natural antibacterial molecules alone or in combination with antibiotics. The main conclusion is that terrestrial biota-derived antibacterial products and substances open a variety of new ways for modern improved therapeutic strategies. New terrestrial sources of known antibacterial agents and new antibacterial agents from terrestrial biota were discovered during the last 5 years, which are under investigation together with some long-ago known but now experiencing their renaissance for the development of new medical treatments. The use of natural antibacterial peptides as well as combinational therapy by commercial antibiotics and natural products is outlined as the most promising method for treating bacterial infections. In vivo testing and clinical trials are necessary to reach clinical application.

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Studying the Bioactive Components and Phytochemicals of the Methanol Extract of Rhanterium epapposum Oliv.

Cited by 3 publications

References 16 publications

In Vitro Propagation and Phytochemical Composition of Centratherum punctatum Cass—A Medicinal Plant

In Vitro Propagation and Phytochemical Composition of Centratherum punctatum Cass—A Medicinal Plant

Polyphenols of the Inuleae-Inulinae and Their Biological Activities: A Review

Recent Progress in Terrestrial Biota Derived Antibacterial Agents for Medical Applications

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