Study The Effect of Chamomile and Garcinia herbs on Obese Rats

Abstract

This study aimed to investigate the effect of chamomile (Matricaria chamomilla), garcinia (Garcinia cambogia) and mixture of both on male obese rats. Thirty (30) adult male Sprague Dawley rats were divided into five groups. Group (1): Normal rats fed on basal diet as control negative (C-), Group (2): Control positive (C+) (untreated group). Group (3): Obese rats fed on basal diet and Chamomile (5%). Group ( 4): Obese rats fed on basal diet and Garcinia (5%). Group ( 5): Obese rats fed on basal diet and mixture of both (5%). At the end of experiment, after 28 days of feeding, all serum samples were analyzed for biochemical parameters. Body weight gain , feed intake and feed efficiency ratio also calculated. Obesity led to a significant (P ≤ 0.05) decrease in the level of HDL & AST/ALT while a significant (P ≤ 0.05) increase was recorded in TC, TG, VLDL, LDL, AI, U.A, Creatinine, Urea, GOT, GPT, ALP & Glucose. Obese rats were fed on different diets and the results showed amarked improvement in all the different indicators.Improvement was more pronounced for garcinia compared to chamomile diets, and the best group was recorded for the mix group, indicating a synergistic action. It is therefore recommended to use them as effective treatments in reducing the accumulation of harmful fat in the body and reducing weight.