Study Significance of Low Plasma Homocysteine or Hypohomocysteinemia and Some Parameter to Syndrome Associated with COVID-19 in Basrah City, Iraq

Abstract

The increasing interdependence between the countries of the world has led to an increase in the risks faced by societies in general. The COVID-19 pandemic, for example, has transcended national borders, affecting people regardless of nationality, level of education, income or gender. As for its consequences, it has affected the most vulnerable groups. In this study, we have considered the significance of low plasma homocysteine or hypohomocysteinemia and some parameters of the syndrome associated with COVID-19. Just as an increase in the level of homocysteine in plasma has a negative effect on the heart and blood vessels, its decrease may put the health of those who suffer from it at risk. Homocysteine is known to be the natural mediator of the conversion of methionine to cysteine; hence, the danger, as the latter is necessary for the production of glutathione, taurine and sulphate. In this study, homocysteine and some indicators of COVID-19 syndrome were examined using ELISA kit and other methods. The homocysteine level in the serum of people who recovered from COVID-19 was found to be lower than in normal and healthy people. Thus, it indicates that people who have been cured may suffer from hypohomocystinemia. We also study some parameters, such as ALP, GOT, GPT, Glucose level and HDL, cholesterol. The results showed a significant decrease in the level of GOT enzyme and HDL level.