Study on thermoplastic polyurethane/polypropylene (TPU/PP) blend as a blood bag material

Ajili, Shadi Hassan; Ebrahimi, Nadereh Golshan; Khorasani, Mohammad Taghi

doi:10.1002/app.12180

Cited by 46 publications

(43 citation statements)

References 25 publications

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“…21,22 However, surface-induced thrombosis, protein fouling, and cytocompatibility are three serious consequences when using PUs as blood-contacting materials in hemodialysis. 23,24 The most popular method for improving the anticoagulative is the modification of the materials themselves into antithrombogenic materials. 25 The synthesis of novel blood-compatible materials has been drawing wide attention.…”

Section: Introductionmentioning

confidence: 99%

Novel blood‐compatible waterborne polyurethane using chitosan as an extender

Meng

Han

et al. 2008

J of Applied Polymer Sci

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A series of novel block polymers of polyurethane (PU) and chitosan have been prepared in two steps. The first step is the preparation of PU prepolymer, obtained from polytetramethylene oxide glycol (PTMO, M n 5 1000), isophrone diisocyanate (IPDI), and 2,2 0 -dimethylol propionic acid (DMPA), followed by ionizing PU prepolymer with triethylamine (TEA). The second step involves PU chain-extended by water-soluble chitosan of low molecular weight (M n 5 5000) by self-emulsion polymerization method. The sizes of the latex particles, morphology, and copolymer architecture have been characterized by dynamic light scattering (DLS), general tensile test, infrared spectroscopy (IR), surface contact angle measurement, and transmission electron microscopy (TEM). Furthermore, it shows that the addition of chitosan remarkably increases anticoagulative property of PU elastomers confirmed by the recalcification time.

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Section: Introductionmentioning

confidence: 99%

Novel blood‐compatible waterborne polyurethane using chitosan as an extender

Meng

Han

et al. 2008

J of Applied Polymer Sci

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“…In general, thermoplastic polyurethanes (PUs) are considered to offer relatively good hemocompatibility and mechanical properties when compared to the other synthetic materials (e.g., poly(vinyl chloride) and silicone rubber) [20][21][22]. Indeed, they have been used to prepare a variety of medical devices including blood bags, catheters, vascular grafts, and portions of artificial hearts [23,24]. However, PUs are not completely thromboresistant, as platelet adhesion/activation can still occur when in contact with blood for extended periods of time [21,[25][26][27].…”

Section: Introductionmentioning

confidence: 99%

Polyurethane with tethered copper(II)–cyclen complex: Preparation, characterization and catalytic generation of nitric oxide from S-nitrosothiols

Hwang

Meyerhoff

2008

Biomaterials

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The preparation and characterization of a commercial biomedical grade polyurethane (Tecophilic, SP-93A-100) material possessing covalently linked copper(II)-cyclen moieties as a nitric oxide (NO) generating polymer are described. Chemiluminescence NO measurements demonstrate that the prepared polymer can decompose endogenous S-nitrosothiols (RSNOs) such as S-nitrosoglutathione and S-nitrosocysteine to NO in the presence of thiol reducing agents (RSHs; e.g., glutathione and cysteine) at physiological pH. Since such RSNO and RSH already exist in blood, the proposed polymer is capable of spontaneously generating NO when in contact with fresh blood. This is demonstrated by utilizing the polymer as an outer coating at the distal end of an amperometric NO sensor to create a device that generates response toward the RSNO species in the blood. This polymer possesses the combined benefits of a commercial biomedical grade polyurethane with the ability to generate biologically active NO when on contact with blood, and thus may serve as a useful coating to improve the hemocompatibility of various medical devices.

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“…At the TPU/PP blend ratio of 80/ 20, it was observed that the size of the dispersed phase was smaller than those at the other blend ratios. When the size of the dispersed phase decreased, the interfacial tension between two phases decreased, resulting in better compatibility between the two phases (Ajili et al, 2003). The blend morphologies of TPU/PP blend at the ratio of 60/40 and 50/50 exhibited a co-continuous phase as presented in Fig.…”

Section: Resultsmentioning

confidence: 96%

“…On the other hand, impact strength, adhesion and paintability of polyolefins are also enhanced by blending with TPU (Lu et al, 2003). In addition, due to environmental and safety reasons, blends between TPU and polypropylene (PP) attract more interest as a replacement of poly(vinyl chloride) (Ajili et al, 2003). TPU/PP blends are known to be immiscible resulting in some inferior mechanical properties.…”

Section: Introductionmentioning

confidence: 98%

Reactive Blending of Thermoplastic Polyurethane and Polypropylene

Jaruttrakool

Tanpichai

Pentrakoon

et al. 2010

International Polymer Processing

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In this research, reactive blending of thermoplastic polyurethane (TPU) and polypropylene (PP) was studied. Grafting of maleic anhydride (MAH) onto TPU/PP blends was performed by a twin-screw extruder in the presence of dicumyl peroxide (DCP). Mechanical properties and morphology of the blends were investigated by tensile testing and scanning electron microscopy (SEM), respectively. Thermal properties of the blends were characterized by differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA). The obtained results were compared with those of the uncompatibilized blends and the blends compatibilized with a commercial maleic anhydride grafted polypropylene (PP-g-MA). The results from the uncompatibilized blends clearly indicate that the TPU and PP are immiscible resulting in undesirable properties of the blends. These properties were improved significantly when TPU and PP were reactive-blended in the presence of MAH and DCP. When comparing with the blends compatibilized with PP-g-MA, the blends prepared by the reactive blending technique possessed better mechanical properties.

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Study on thermoplastic polyurethane/polypropylene (TPU/PP) blend as a blood bag material

Cited by 46 publications

References 25 publications

Novel blood‐compatible waterborne polyurethane using chitosan as an extender

Novel blood‐compatible waterborne polyurethane using chitosan as an extender

Polyurethane with tethered copper(II)–cyclen complex: Preparation, characterization and catalytic generation of nitric oxide from S-nitrosothiols

Reactive Blending of Thermoplastic Polyurethane and Polypropylene

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