Study on the validity of 3 × 3 Mueller matrix decomposition

Wang, Yunfei; Guo, Yige; Zeng, Nan; Chen, Dongsheng; He, Honghui; Ma, Hui

doi:10.1117/1.jbo.20.6.065003

Cited by 20 publications

(15 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The anisotropic biological elements in the ECM (particularly collagen and elastin) have been simulated with several materials, including silk 88,99 and glass fibers. 98,107 An example of fibrous phantom is shown in Fig. 3.…”

Section: Retarding Phantomsmentioning

confidence: 99%

Optical phantoms for biomedical polarimetry: a review

et al. 2019

View full text Add to dashboard Cite

Calibration, quantification, and standardization of the polarimetric instrumentation, as well as interpretation and understanding of the obtained data, require the development and use of well-calibrated phantoms and standards. We reviewed the status of tissue phantoms for a variety of applications in polarimetry; more than 500 papers are considered. We divided the phantoms into five groups according to their origin (biological/nonbiological) and fundamental polarimetric properties of retardation, depolarization, and diattenuation. We found that, while biological media are generally depolarizing, retarding, and diattenuating, only one of all the phantoms reviewed incorporated all these properties, and few considered at least combined retardation and depolarization. Samples derived from biological tissue, such as tendon and muscle, remain extremely popular to quickly ascertain a polarimetric system, but do not provide quantifiable results aside from relative direction of their principal optical axis. Microspheres suspensions are the most utilized phantoms for depolarization, and combined with theoretical models can offer true quantification of depolarization or degree of polarization. There is a real paucity of birefringent phantoms despite the retardance being one of the most interesting parameters measurable with polarization techniques. Therefore, future work should be directed at generating truly reliable and repeatable phantoms for this metric determination. Diattenuating phantoms are rare and application-specific. Given that diattenuation is considered to be low in most biological tissues, the lack of such phantoms is seen as less problematic. The heterogeneity of the phantoms reviewed points to a critical need for standardization in this field. Ultimately, all research groups involved in polarimetric studies and instruments development would benefit from sharing a limited set of standardized polarimetric phantoms, as is done earlier in the round robin investigations in ellipsometry.

show abstract

Section: Retarding Phantomsmentioning

confidence: 99%

Optical phantoms for biomedical polarimetry: a review

et al. 2019

View full text Add to dashboard Cite

show abstract

“…The assumptions -especially the latter two -cannot be satisfied in many cases, especially for anisotropic tissues. Based on Monte Carlo simulation and tissue phantom studies, Wang et al assessed the difference between the results obtained from 3 3 3 Mueller matrix decomposition [204] and 4 3 4 Mueller polar decomposition [205], and found that the parameters derived from the 3 3 3 Mueller matrix decomposition are usually not the same as those from the 4 3 4 Mueller matrix decomposition but demonstrate similar qualitative relations to changes in the microstructure of the sample, such as the density, size, and orientation distributions of the scatterers, and birefringence of the interstitial medium. Another emerging interpretation method named "Mueller matrix transformation method" introduced in Section 5.3 may be more promising to extract the useful linear depolarization and retardance related information of tissue from 3 3 3 Mueller matrix images.…”

Section: 3 3 Mueller Polarimetric Endoscopementioning

confidence: 99%

Mueller polarimetric imaging for surgical and diagnostic applications: a review

2017

View full text Add to dashboard Cite

Polarization is a fundamental property of light and a powerful sensing tool that has been applied to many areas. A Mueller matrix is a complete mathematical description of the polarization characteristics of objects that interact with light, and is known as a transfer function of Stokes vectors which characterise the state of polarization of light. Mueller polarimetric imaging measures Mueller matrices over a field of view and thus allows for visualising the polarization characteristics of the objects. It has emerged as a promising technique in recent years for tissue imaging, improving image contrast and providing a unique perspective to reveal additional information that cannot be resolved by other optical imaging modalities. This review introduces the basis of the Stokes-Mueller formulism, interpretation methods of Mueller matrices into fundamental polarization properties, polarization properties of biological tissues, and considerations in the construction of Mueller polarimetric imaging devices for surgical and diagnostic applications, including primary configurations, optimization procedures, calibration methods as well as the instrument polarization properties of several widelyused biomedical optical devices. The paper also reviews recent progress in Mueller polarimetric endoscopes and fibre Mueller polarimeters, followed by the future outlook in applying the technique to surgery and diagnostics. Tissue polarization properties convey morphological, micro-structural and compositional information of tissue with great potential for label free characterization of tissue pathological changes. Recent progress in tissue polarimetric imaging and polarization resolved endoscopy paved the way for translation of polarimetric imaging to surgery and tissue diagnosis.

show abstract

“…However, it is not trivial to take the 4 × 4 Mueller matrices at different wavelengths using the current experimental setup. Also, decomposition of the 3 × 3 Mueller matrix results shows large discrepancies in the set of parameters [27]. Therefore, we use the MMT parameters A and b, which are only linked to the linear polarization Mueller matrix elements, i.e.…”

Section: Mueller Matrix Transformation (Mmt) Parametersmentioning

confidence: 99%

Characterizing microstructures of cancerous tissues using multispectral transformed Mueller matrix polarization parameters

He¹,

He²,

Chang³

et al. 2015

Biomed. Opt. Express

Self Cite

112

View full text Add to dashboard Cite

Abstract:In this paper, we take the transmission 3 × 3 linear polarization Mueller matrix images of the unstained thin slices of human cervical and thyroid cancer tissues, and analyze their multispectral behavior using the Mueller matrix transformation (MMT) parameters. The experimental results show that for both cervical and thyroid cancerous tissues, the characteristic features of multispectral transmitted MMT parameters can be used to distinguish the normal and abnormal areas. Moreover, Monte Carlo simulations based on the sphere-cylinder birefringence model (SCBM) provide additional information of the relations between the characteristic spectral features of the MMT parameters and the microstructures of the tissues. Comparisons between the experimental and simulated data confirm that the contrast mechanism of the transmission MMT imaging for cancer detection is the breaking down of birefringent normal tissues for cervical cancer, or the formation of birefringent surrounding structures accompanying the inflammatory reaction for thyroid cancer. It is also testified that, the characteristic spectral features of polarization imaging techniques can provide more detailed microstructural information of tissues for diagnosis applications. properties and effect of wavelength choice on differentiation between ex vivo normal and cancerous gastric samples," J.

show abstract

Study on the validity of 3 × 3 Mueller matrix decomposition

Cited by 20 publications

References 26 publications

Optical phantoms for biomedical polarimetry: a review

Optical phantoms for biomedical polarimetry: a review

Mueller polarimetric imaging for surgical and diagnostic applications: a review

Characterizing microstructures of cancerous tissues using multispectral transformed Mueller matrix polarization parameters

Contact Info

Product

Resources

About