Study on the Metabolism of Sesamin to Ethanol and the Preparation of Sesamin Microcapsules

Abstract

Hydroxyl radicals were obtained by simulating ethanol metabolism in vitro. The absorbance of sesamin was measured by reacting with sesamin solutions of different concentrations. The ability of sesamin sample to scavenge hydroxyl radicals decreased with the increase of dilution ratio in a certain range. A comparative experiment between sesamin and water was designed to verify that sesamin has a significant promoting effect on alcohol dehydrogenase (ADH). The results showed that sesamin could promote the metabolism of ethanol. It indicated that the sesamin can dispel alcohol and protect the liver. In addition, the sesamin was encapsulated by the coacervation method to optimize the preparation method of sesamin microcapsules, which laid a foundation for the practical application of sesamin.

Byproducts of Sesame Oil Extraction: Composition, Function, and Comprehensive Utilization

“…The prototype of osteogenic tissue engineering is prepared from polyhexene and sesamin via the electrospinning technique, and this prototype can be applied to biomedicine [ 106 ]. Based on the fact that sesamin can improve the activity of alcohol dehydrogenase, sesamin microcapsules are prepared via the agglomeration method so as to promote the commercial application of sesamin [ 107 ]. The extent, rate, and variability of the oral administration absorption of sesamin could be controlled using different types of lipid-based formulations (LBFs), indicating the possibility of developing better oral sesamin supplement products using appropriate formulations [ 108 ].…”