Study on the mechanism of zinc finger proteins ROCK1 and DMD in zinc-mediated cognitive impairment caused by aluminum exposure
Nan Shang,
Xianlin Li,
Lan Zhang
et al.
Abstract:Background: Aluminum (Al) exposure was implicated in neurodegenerative diseases and cognitive impairment, yet the involvement of zinc (Zn) and its mechanism in Al-induced mild cognitive impairment (MCI) remains poorly understood.
Objective: Exploring the role of Zn in Al-induced cognitive impairment and its potential mechanisms.
Methods:
Montreal Cognitive Assessment (MoCA) test scores, and serum Al, Zn from Al industry workers were collected. A mediation analysis was performed to evaluate the role of serum Zn… Show more
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