2014
DOI: 10.1016/j.saa.2013.11.113
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Study on the interaction between 4-thio-5-methyluridine and human serum albumin by spectroscopy and molecular modeling

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Cited by 23 publications
(10 citation statements)
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“…HSA is a subject of much research, especially in the study of drug and protein interactions [1]. The interaction of small molecules with serum albumin is of great importance from both a qualitative and quantitative point of view because the distribution and metabolism of all kinds of small molecules correlate with their binding affinities toward serum albumin in blood [2].…”
Section: Introductionmentioning
confidence: 99%
“…HSA is a subject of much research, especially in the study of drug and protein interactions [1]. The interaction of small molecules with serum albumin is of great importance from both a qualitative and quantitative point of view because the distribution and metabolism of all kinds of small molecules correlate with their binding affinities toward serum albumin in blood [2].…”
Section: Introductionmentioning
confidence: 99%
“…To confirm the quenching mechanism induced by cefepime hydrochloride, fluorescence quenching data are analyzed with the Stern-Volmer equation (Equation 1) [26][27][28][29][30][31][32][33][34][35][36][37]:…”
Section: Resultsmentioning
confidence: 99%
“…By comparing curve c with curve d, an obvious spectral change was observed, indicating a static quenching mechanism with the formation of Q-dots-DA complex. For a static quenching, the binding constant (Ka) for the interaction of thioglycolic acid-wrapped CdTe/CdS Q-dots and DA could be obtained by using the Lineweaver-Burk equation [34]: …”
Section: Methodsmentioning
confidence: 99%