Study on the interaction between palladium(II)–lincomycin chelate and erythosine by absorption, fluorescence and resonance Rayleigh scattering spectra and its analytical applications

Abstract

In pH 5.0-5.4 HAc-NaAc buffer solution, lincomycin (Linco) reacted with Pd(II) to form 1:1 cationic chelate, which could further react with erythrosine (Ery) to form 1:1 ion-association complexes (Pd-Linco)Ery. As a result, not only were the absorption and fluorescence spectra changed, but also the resonance Rayleigh scattering (RRS) intensity was greatly enhanced. These phenomena offered useful means for the determination of Linco by spectrophotometry, fluorescence and RRS methods. The linear range and detection limit of Linco were 0.20-3.00 mg/mL and 0.057 mg/mL, 0.20-4.80 mg/mL and 0.061 mg/mL, 0.05-2.70 mg/mL and 0.015 mg/mL for the spectrophotometric, fluorescence quenching and RRS methods, respectively. Among these, the RRS method obtained the highest sensitivity. Therefore, the optimum reaction conditions and the influences of coexisting substances were investigated using the RRS method. A simple, sensitive and rapid method has been developed for the determination of Linco in either the pharmaceutical form or human body fluids, and the reasons for RRS enhancement are discussed.

Resonance Rayleigh‐scattering spectral method for the determination of some aminoglycoside antibiotics using CdTe quantum dots as a probe

“…(7) Resonance Rayleigh scattering (RRS) technique as an analytical method has received increasing interest due to its high sensitivity, convenience in performance, simplicity, and rapidity. Therefore, in recent years RRS method has been proposed for the determination of nucleic acids, (8)(9)(10) proteins, (11,12) inorganic ions, (13,14) pharmaceuticals, (15)(16)(17)(18)(19)(20) etc. These RRS techniques are usually based on the enhanced RRS signals resulting from binding of chromophoers to analytes; nevertheless the chromopores used, was synthetic porphyins, biological dyes, surfactants, and so on.…”

Determination of Meclofenoxate Hydrochloride by Resonance Rayleigh Scattering Method Coupled with Flow Injection Technique

“…Resonance Rayleigh scattering (RRS), as a new analytical technique, is attracting more and more attention due to its high sensitivity and simplicity. In recent years, RRS has become an active research field of spectral analysis and has been widely applied to the study and determination of biological macromolecules such as nucleic acids, proteins, heparin, metal ions, nonmetal ions, and nanoparticle (Wang 2002), and it also shows good application prospect in medicine analysis (Qin et al 2009;Yi et al 2009). Flow injection analysis (FIA) technique is characterized by inexpensive yet highly flexible instrumentation, fast response, high sample throughput, and low consumption of reagents.…”

Determination of Promethazine Hydrochloride with Palladium(II) and Na2WO4by Resonance Rayleigh Scattering and Resonance Nonlinear Scattering Spectra

“…[29][30][31][32][33][34][35][36][37] Our experiments found that at room temperature and pH 4.6-5.3 Britton-Robinson (BR) buffer medium, Pd(II) reacted with PMZ to form 1:2 cationic chelate [Pd(PMZ) 2 ] 2þ , which further reacted with Na 2 WO 4 to form a 1:1 ternary ion-association complex ([Pd(PMZ) 2 ] Á (WO 4 )) and RRS, SOS, FDS were increased rapidly. The maximum RRS, SOS, and FDS wavelengths of ternary ion-association complex were located at 310 nm, 570 nm and 391 nm, respectively.…”