Study on the Efficacy of Electric Acupuncture in the Treatment of Premature Ejaculation Based on Testosterone Level

Abstract

Objective. To investigate the clinical efficacy and possible mechanism of electroacupuncture in the treatment of premature ejaculation. Methods. 50 cases of premature ejaculation patients who met the diagnostic criteria were randomly divided into 2 groups with 25 cases in each group. The observation group was treated with electroacupuncture, and the control group was treated with Longdan Xiegan decoction. The treatment period was 4 weeks. Ejaculation latency (IELT), sexual satisfaction score of patients, sexual satisfaction score of partners, testosterone test, and drug safety assessment were performed in all 4 groups before and after treatment. Results. IELT was prolonged in all groups after treatment, the difference was statistically significant ( P < 0.05 ). At the same time, the IELT of the observation group was significantly higher than that of the control group after treatment. Life satisfaction scores of patients and spouses in 2 groups were improved after treatment compared with before treatment, the difference was statistically significant ( P < 0.05 ). After treatment, the satisfaction scores of patients and spouses in the observation group were higher than those in the control group, and the difference was statistically significant ( P < 0.05 ). Before treatment, there was no significant difference in serum testosterone levels among all groups ( P > 0.05 ). Serum testosterone levels in all groups were decreased after treatment compared with before treatment, with statistical significance ( P < 0.05 ). After treatment, the serum testosterone level of the observation group was lower than that of the control group, and the difference was statistically significant ( P < 0.05 ). During the treatment, the adverse reactions in each group disappeared after treatment, and no obvious abnormality was observed in the safety indicators. Conclusion. Electroacupuncture can improve the symptoms of premature ejaculation, which may be related to the regulation of serum testosterone by acupuncture.

Traditional, Complementary and Alternative Medicines in the Treatment of Ejaculatory Disorders: A Systematic Review

“…The data extracted from the included studies are summarized in Table 1 based on the type of intervention provided. Proportionately, 31.8% (n = 7) investigated different lifestyle, exercise and/or physical activities [ 58 , 59 , 60 , 61 , 62 , 63 , 64 ]; 22.7% (n = 5) investigated herbal medicine supplements [ 65 , 66 , 67 , 68 , 69 ]; 18.2% (n = 4) investigated topical herbal applications [ 70 , 71 , 72 , 73 ]; 13.6% (n = 3) investigated acupuncture or electroacupuncture [ 74 , 75 , 76 ]; and 4.5% (n = 1) each investigated vitamin, mineral and/or nutraceutical supplements [ 77 ]; hyaluronic acid penile injection [ 78 ]; and music therapy [ 79 ].…”

“…Of the 22 studies included, 95.5% (n = 21) studies investigated the effect of TCAM treatments on patients with PE [ 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 78 , 79 ], with only 1 study investigating RE [ 77 ]. No studies were identified that investigated TCAM for treating DE, anejaculation or other EjDs.…”

“…No studies were identified that investigated TCAM for treating DE, anejaculation or other EjDs. Of the 21 studies that investigated TCAM in PE, most used the IELT as a primary outcome measure [ 58 , 59 , 60 , 62 , 63 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 78 , 79 ]. Furthermore, 42.9% (n = 9) used the PEDT alongside IELT [ 59 , 62 , 66 , 68 , 73 , 74 , 76 , 79 ] or as a primary outcome [ 61 ], 9.5% (n = 2) of studies used the PEP alongside IELT [ 67 ] or as a primary outcome [ 61 ], and 9.5% (n = 2) used the CIPE-5 alongside IELT [ 69 , 70 ].…”

“…The sham acupuncture group was used in two studies investigating acupuncture treatment [ 74 , 76 ], which was further compared to paroxetine [ 74 ] or dapoxetine [ 76 ]. Longdan Xiegan was used as a comparison group investigating electroacupuncture [ 75 ]. Minimal physical activity or sedentary lifestyle [ 59 ], sexual behavioral treatment [ 66 ] and desensitization therapy [ 70 ] were used as a comparison in 4.5% (n = 1) of studies each.…”

The efficacy and mechanism of acupuncture in the treatment of male infertility: A literature review

“…However, the acupuncture had a significant stronger ejaculation-delaying effect than sham acupuncture. Studies have shown that EA can improve the symptoms of premature ejaculation by regulating the level of serum testosterone ( 105 ). Although most studies on acupuncture in the treatment of sexual dysfunction have some methodological problems including small sample sizes and lack of blindness, almost all current studies can prove the efficacy of acupuncture in the treatment of sexual dysfunction, at least better than placebo.…”