Study on the Effects of Casticin Against Gm-Induced Oxidative Damage, Serum Chemistry and Mitochondria in Rats
Abstract:Gentamicin (GM) is an important aminoglycoside antibiotic to treat different infections caused by gram-negative bacteria. Mitochondrial dysfunction is considered as a key factor in the pathogenesis of renal disorders, and an important consequence of GM-induced nephrotoxicity that results in structural and functional alteration. Casticin (CAS) is a potential phytochemical having various pharmacological properties. The current investigation was formulated to ascertain the protective effects of CAS on GM induced … Show more
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