Study on the Correlation between different Levels of Patients with Vertebrobasilar Dolichoectasia and Posterior Circulation Blood Perfusion

Wang, Yanshuang; Huang, Jianhui; Qian, Guizhen; Jiang, Shunbin; Chen, Miao

doi:10.1016/j.jstrokecerebrovasdis.2022.106378

Cited by 6 publications

(4 citation statements)

References 10 publications

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“…Some studies have shown that there are significant differences in posterior circulation blood perfusion among different VBD grades [ 10 ]. In order to explore the relationship between VBD grades and PCF volume, VBD patients were graded by BA bifurcation or BA offset.…”

Section: Discussionmentioning

confidence: 99%

“…VBD mainly shows abnormal extension, expansion and bending of vertebral basilar artery, which can compress brain tissues such as cranial nerve, cerebellum and brain stem, showing changes such as cerebral nerve stimulation and posterior circulation ischemia. Although hemorrhagic cerebrovascular disease caused by VBD is relatively rare, but once hemorrhagic stroke occurs, its symptoms are serious and the prognosis is worse [ [5] , [6] , [7] , [8] , [9] , [10] ]. At present, there are few studies on the etiology of VBD.…”

Section: Introductionmentioning

confidence: 99%

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Study on the relationship between vertebrobasilar dolichoectasia and posterior cranial fossa space

Fanji¹,

Ye²,

Li³

et al. 2023

Heliyon

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Study on the relationship between vertebrobasilar dolichoectasia and posterior cranial fossa space

Fanji¹,

Ye²,

Li³

et al. 2023

Heliyon

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“…Similarly, hearing loss has been reported as one of the main symptoms in patients with BA dolichoectasia, whose BA diameter is excessively dilated by vascular remodeling [ 39 , 40 ]. Wang et al suggested that mural thrombi and atherosclerotic plaques generated by slowed blood flow and turbulence in dilated and tortuous vessels could cause changes in the hemodynamics of the posterior circulation [ 41 ]. By indirectly proving the etiological value of the NLR in this study, we believe that it could be helpful to interpret the results of previous and future studies of NLR values in idiopathic SSNHL in terms of the vascular etiology.…”

Section: Discussionmentioning

confidence: 99%

Correlation of Neutrophil-to-Lymphocyte Ratio and the Dilation of the Basilar Artery with the Potential Role of Vascular Compromise in the Pathophysiology of Idiopathic Sudden Sensorineural Hearing Loss

Kang

Kim

Sunwoo

2022

JCM

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Idiopathic sudden sensorineural hearing loss (SSNHL) currently lacks a clear etiology, as well as an effective treatment. One of the most probable explanations for SSNHL is impairment of the cochlear blood flow. However, dissimilar to a fundoscopic examination, direct observation of cochlear blood vessels is not possible. To indirectly support an ischemic etiology of SSNHL, we investigated whether the degree of initial hearing loss is associated with two atherosclerotic risk factors: dilatation of the basilar artery (BA) and a chronic subclinical inflammatory status measured by the neutrophil-to-lymphocyte ratio (NLR). This retrospective study collected data from 105 consecutive patients diagnosed with idiopathic SSNHL. Then, the patients were divided into two groups according to their NLR as “abnormally high NLR (>3.53, n = 22)” and “NLR within the normal range (0.78–3.53, n = 83)”. The BA diameter and severity of initial hearing loss were significantly correlated with each other in the abnormally high NLR group (p < 0.001). However, there was no significant correlation between initial hearing loss and the BA diameter in the normal NLR group (p = 0.299). Therefore, the NLR may serve as a marker for SSNHL of vascular etiology and a rationale for magnetic resonance imaging examinations based on the pathophysiology.

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“…Most cases of VBD are asymptomatic and diagnosed incidentally (13). When VBD causes elongation and dilation, vertebrobasilar arteries will be distorted, and the blood flow velocity will be reduced and become symptomatic, presenting either with vascular symptoms such as episodes of transient ischemic attacks, ischemic strokes, subarachnoid hemorrhages or with compressive symptoms related to brainstem or cranial nerve compression (Figures 1A,B) (1,5,(14)(15)(16)(17). Of the above symptoms, brainstem and cerebellar ischemia are common, and rupture is uncommon (15,(18)(19)(20).…”

Section: Introductionmentioning

confidence: 99%

Prospects and Dilemmas of Endovascular Treatment for Vertebrobasilar Dolichoectasia

Wang¹,

Yu²

2022

Front. Neurol.

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Vertebrobasilar dolichoectasia (VBD) is characterized by significant expansion, elongation, and tortuosity of the basilar artery and vertebral artery. Certain highly selected cases of VBD can require intervention. Recent advances in endovascular treatment (EVT) have renewed hope for patients with VBD. However, which cases of VBD can benefit from EVT still needs to be determined. Currently, little is known regarding this matter. Therefore, we performed a review of the literature from a PubMed search and cataloged our experience regarding the classification and natural history of VBD and the prospects, prognosis and complications of EVT. The findings can be summarized as follows: for asymptomatic VBD, “wait and see” or medical management may be a reasonable strategy. EVT may only be effective in certain patients. For saccular aneurysms in VBD, especially ruptured aneurysms, EVT is reasonable. For fusiform aneurysms in VBD, EVT can carry high complication rates and should be recommended with caution. For stenting reconstruction in VBD, the effect is uncertain. For the future of EVT of VBD, randomized controlled trials and the development of neurointerventional products are worth pursuing, but EVT in VBD still has a long way to go.

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Study on the Correlation between different Levels of Patients with Vertebrobasilar Dolichoectasia and Posterior Circulation Blood Perfusion

Cited by 6 publications

References 10 publications

Study on the relationship between vertebrobasilar dolichoectasia and posterior cranial fossa space

Study on the relationship between vertebrobasilar dolichoectasia and posterior cranial fossa space

Correlation of Neutrophil-to-Lymphocyte Ratio and the Dilation of the Basilar Artery with the Potential Role of Vascular Compromise in the Pathophysiology of Idiopathic Sudden Sensorineural Hearing Loss

Prospects and Dilemmas of Endovascular Treatment for Vertebrobasilar Dolichoectasia

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