Study on the antioxidant activity and quantification of thioamides based on nitrogen five-membered heterocycles by the kinetic technique

Progress in intermolecular and intramolecular reactions of thioamides with diazo compounds and azides

“…Thioamides exhibit wide range of biological properties such as antifungal [1], antioxidant [2,3] and anticonvulsant [4] activities. Some of them strongly inhibit phosphoglycerate dehydrogenase [5].…”

“…4-Carbimino-1,2,3-thiadiazoles 48 (R 3 = HC = NR) formed by reaction of 4-formyl-1,2,3-thiadiazole with amines, are labile and rearrange to 1,2,3-triazol-4-carbothioamides 50 under the conditions used for their generation[39,40]. It was found that interaction of 1,2,3-thiadiazolylhydrazones of acetophenones with phosphorus pentachloride in benzene or toluene leads to 5H-[1,2,3]triazolo[5,1-b][1,3,4] thiadiazines 51. The reaction most likely involves Dimroth-type rearrangement of the thiadiazole ring into a triazole followed by intramolecular cyclization of Me and SH groups after treatment with PCl 5[41].…”

Humic acid catalyzed solvent-free green protocol for synthesis of thioamide

“…Thioamides are vastly used functional groups for sulfur containing natural products, heterocycles and biologically active compounds 7 with diverse pharmacological activities such as antibacterial 8 , antioxidant 9 , antithyroid 10 , antiulcerative 11 , aldose reductase inhibitor 12 , antifungal 13 , antimycobacterial 14 , anticonvulsant 15 , spasmolytic 16 , inhibitor of estrogen receptor 17 and anticancer 18 .…”

The comparative electrochemistry of 2-mercaptothiazoline when using gold/quartz and modified silver/quartz electrodes, and its application in a flow-through voltammetric sensor

“…[3][4][5] It is an important mercapto-containing vemembered heterocyclic compound used in both pharmaceutical and synthetic organic chemistry. [6][7][8][9][10][11][12][13] There has been a wide study on its antioxidant and antibiotic activities. Also, it has been designed and synthesized from thiazolidine derivatives with potential biological activities.…”