Study on Some Clinical, Biochemical Characteristics and Outcome of Bacterial Meningitis Due to Streptococcus Suis at Hue Central Hospital 2011-2012

Abstract

Objectives: Bacterial meningitis is a very severe infectious disease in Vietnam. Studies about bacterial meningitis in our country in the last 10 years show that the most isolated causing bacteria is Streptococcus suis. Materials and methods: Prospective study. All the patients over 15 years old with diagnosis bacterial meningitis due to S. suis treated in Hue Central Hospital from May, 2011 to April, 2012 were recruited in this study. Results: 40 patients were enrolled in this study (male: 82.5%, female: 17.5%). Mean age 46.5 ± 17.72. 45% of patients had contact to pig or used pigs products. Related diseases: ENT diseases (25%), cranial trauma (5%), diabetes (7.5%), ect. The majority of patients have headache (97.5%), vomiting (85%), Kernig’s sign (72.5%), Brudzinsky’s sign (52.5%). 45% of patients have CRP 100 - 200 mg/L. 55% of patients have over 1000 cells/mm3 CSF, 47.5% of patients have CSF protein 3.0 ­– 5.0 g/L. In the result: 100% patients recovered, 40% had complications. Deefness was the most founded complication (37.5%). Conclusions: 45% of patients had contact to pig or used pigs products. The majority of patients have headache (97.5%), vomiting (85%), Kernig’s sign (72.5%), Brudzinsky’s sign (52.5%). Deefness was the most founded complication (37.5%). Key words: Meningitis, Streptococcus suis