Study on simultaneous speciation of arsenic and antimony by HPLC–ICP-MS

Speciation of antimony (III) and antimony (V) using hydride generation for meglumine antimoniate pharmaceutical formulationsquality control

“…Several methodologies have been used for Sb(V) and Sb(III) quantification in different matrices. However herein the HG-ICP-AES technique was used for the first time to evaluate a new pharmaceutical formulation quality presenting these species (Apte & Howard 1986, Casiot et al 1998, Cava-Montesinos et al 2003, González et al 2005, Morita et al 2007.…”

“…There are several methods to separate simultaneously and quantify the species Sb(III) and Sb(V) in the pharmaceutical formulations such as: capillary electrophoresis -inductively coupled plasma mass spectrometry (CE-ICP-MS) (Michalke & Schramel 1999); high performance liquid chromatography hydride generation-atomic fluorescence spectrometry detection (HPLC-HG-AFS) (Apte & Howard 1986, Casiot et al 1998, Cava-Montesinos et al 2003, González et al 2005, Morita et al 2007); spectrophotometric methods with flow injection (Bloomfield et al 1992, Rath et al 1997, Trivelin et al 2006; high performance liquid chromatography-hydride generation-atomic absorption spectrometry detection (HPLC-HG-AAS) (Smichowski et al 1995, Lintschinger et al 1997, Zhang et al 1998, Lindemann et al 1999, Zheng et al 2000; and ICP-MS (Lintschinger et al 1998, Ulrich 1998a, b, Zheng et al 2001. Even though these methods are the most appropriate for speciation of antimony, they are poorly suitable for the employment in the routine of medication quality control, which demands simple and more affordable methods.…”

Highly Sensitive Voltammetric Speciation and Determination of Inorganic Arsenic in Water and Alloy Samples Using Ammonium 2‐Amino‐1‐Cyclopentene‐1‐Dithiocarboxylate

“…Various methods have been used for the determination of arsenic at the trace level including spectrophotometric [9 -11], atomic absorption and fluorescence spectroscopy [12 -17] and inductively coupled plasma-mass spectrometry (ICP-MS) [18,19]. The spectrophotometric methods are insensitive, suffer from many interferences, need organic solvents for extraction, have unsatisfactory detection limits, and exhibit poor reproducibility.…”

Heat-treated Saccharomyces cerevisiae for antimony speciation and antimony(III) preconcentration in water samples

“…Sb(III) is considered to be more toxic than Sb(V) [1]. Separation and quantification of these species can be performed by high performance liquid chromatography (HPLC) coupled to atomic absorption spectrometry (AAS), atomic fluorescence spectrometry (AFS) or inductively coupled plasma optical emission/mass spectrometry (ICP-OES/MS) [4][5][6][7][8][9]. To achieve the required limit of detection, hydride generation (HG) is generally added as postcolumn derivatization to preconcentrate the species and allow their separation from the matrix.…”