Study on Properties of Inclusion Complexation of Triclopyr Butoxy Ethyl Ester with Mixed Surfactant System

Abstract

b-cyclodextrin exhibits the property of forming inclusion complexes with various molecules. These complexes display improved properties in comparison with starting molecules in terms of their solubility and stability. In the present study, triclopyr butoxy ethyl ester, a selective systemic herbicide was utilized for forming inclusion complexes with b-cyclodextrin in absence and presence of the nonionic: lauric acid monoethanolamide (C 12 MEA)/anionic: a-olefin sulfonate (AOS) mixed surfactant system. The objective of present work was to study the important physical properties like dissolution rate, dispersion stability and wettability in presence of mixed surfactant systems of inclusion complex of a herbicide. Coprecipitation method was used for inclusion complex formation, which was consequently characterized by analytical techniques such as x-ray diffractometry (XRD), differential scanning calorimetry (DSC) and ultra-violet spectroscopy (UV).