Study on impression smears of hepatic coccidiosis in rabbits

Sivajothi, S.; Reddy, B. Sudhakara; Rayulu, V. C.

doi:10.1007/s12639-014-0602-8

Cited by 17 publications

(22 citation statements)

References 7 publications

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“…Impression smears from the intestinal mucosa also revealed the presence of many oocysts and merozoites along with the inflammatory cells especially macrophages and necrotic cells debris. The findings corroborate with the study on impression smear of hepatic coccidiosis in rabbits earlier reported by Sivajothi et al (2016).…”

Section: Cytologic Interpretationsupporting

confidence: 92%

Clinico-pathologic observations of spontaneous hepatic coccidiosis in broiler rabbits maintained in Bannerghatta biological park in Karnataka state of India

Manjunatha¹,

Rout²,

Sujay³

et al. 2019

IJAR

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The present study reports the clinico-pathologic changes observed in spontaneous hepatic coccidiosis caused by Eimeria stiedae in rabbits at Bannerghatta Biological Park (BBP) in Karnataka state of India. The clinical signs observed in the affected rabbits included sudden death, stunted growth, anorexia, weight loss, diarrhoea and abdominal pain. Increased liver enzymes and bilirubin was noticed upon biochemical examination. At necropsy, lesions included grossly enlarged liver (hepatomegaly) with presence of discrete yellowish-white nodules ranging from 1mm to 5mm size throughout the parenchyma containing a thick creamy white fluid. Faecal sample examination demonstrated the presence of Eimeria oocyts. The impression smears from the liver and intestinal mucosa also showed Eimeria oocysts, degenerative changes, necrotic cells and mononuclear cell aggregation to form oocyst granuloma. Histological observation revealed distension of bile duct, hyperplasia of epithelium along with numerous coccidian oocysts at the centre. Granulomatous tissues were observed to have encircled the bile duct with infiltration of inflammatory cells. Microscopic examination of exudates from liver also revealed numerous oocysts of E. stiedae. Multiple areas of coagulative necrosis of hepatic cells surrounded with inflammatory cells were also found.

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Section: Cytologic Interpretationsupporting

confidence: 92%

Clinico-pathologic observations of spontaneous hepatic coccidiosis in broiler rabbits maintained in Bannerghatta biological park in Karnataka state of India

Manjunatha¹,

Rout²,

Sujay³

et al. 2019

IJAR

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“…The livers and intestines from amprolium and trimethoprimsulfamethoxazole (potentiated sulphonamide) treatment groups had severe gross and microscopic lesions indicating their inability to treat clinical coccidiosis. Gross lesions in these groups were characterized by hepatomegaly, raised yellowish-white multinodular lesions, distended biliary tree filled with viscous to cheesy content, fibrinous strands on the liver surface, congested and hemorrhagic intestines with ballooned sections consistent with those described in previous studies [34,35]. Hyperplasia and cystic enlargement of the bile duct epithelium has been reported to results in the yellowish-white nodular lesions on the liver surface seen in our study [8,28].…”

Section: Effects Of Anticoccidial Drugs On Gross and Histopathologicasupporting

confidence: 88%

Effects of Anticoccidial Drugs on Gross and Histopathological Lesions Caused by Experimental Rabbit Coccidiosis

Ogolla¹,

Okumu²,

Gathumbi³

et al. 2018

SOJVS

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Effects of commonly used anticoccidial drugs in treating lesions caused by intestinal and hepatic coccidiosis have not been described for anticoccidial-drugs used in Kenya. The objective of this study was to describe the effects of four anticoccidial drugs on gross and histopathological lesions caused by artificially-induced mixed Eimeria infection with inoculant dose of E. flavescens (20%), E. perforans (21%), E. intestinalis (9%), E. coecicola (4.2%), E. media (11.2%), E. piriformis (10.6%), E. stidae (16%), and E. Magna (8%). In a controlled laboratory trial, 60 weaner rabbits were randomly allocated to treatment groups A, B, C, D, E and F. Each group had 10 rabbits. Groups A and C served as uninfected-untreated and infecteduntreated control groups, respectively. Groups B, D, E and F were experimentally infected and treated with amprolium, diclazuril, sulfachloropyrazine, and trimethoprim-sulfamethoxazole, respectively. On day 30 post treatment, 3 rabbits from each treatment group were selected randomly and humanely euthanized for gross and microscopic lesion examination. Diclazuril and sulfachloropyrazine treatment groups had significantly minimal to no macroscopic and microscopic lesions. This was consistent with a high efficacy of the drugs in reversing intestinal and hepatic lesions of coccidiosis in rabbits. Rabbits from amprolium, trimethoprim-sulfamethoxazole and infected-untreated control groups presented with severe intestinal and hepatic gross lesions characterized by extensive hepatomegaly, numerous raised hepatic multinodular lesions and marked congestion of the intestines that indicated mild to no effect of the drugs in reversing hepatic and intestinal lesions. Microscopic lesions in rabbits treated with amprolium and trimethoprim-sulfamethoxazole had marked desquamation of intestinal and bile duct epithelium, distended and thickened bile duct, numerous coccidian parasites at different stages of development in duct epithelium and mature oocysts in the intestinal and bile duct lumens; as was in positive control group. Additionally, rabbits from the three treatment groups recorded higher intestinal and hepatic histological lesion scores.

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“…The obtained material was evaluated through macroscopic analysis of each liver and gall bladder and inspected for nodules typical characteristic of infection with Eimeria stiedae followed by liver smear treatment (Sivajothi et al 2014). Histopathologically, intestines of the dead rabbits were thoroughly examined for the gross lesions and specimens were collected in 10% formalin.…”

Section: Species Identificationmentioning

confidence: 99%

An Epidemiological Study on Endoparasites of Domestic Rabbits (Oryctolagus cuniculus) in Egypt with Special Reference to Their Health Impact

Elshahawy¹,

El-Goniemy²

2018

JSM

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Study on impression smears of hepatic coccidiosis in rabbits

Cited by 17 publications

References 7 publications

Clinico-pathologic observations of spontaneous hepatic coccidiosis in broiler rabbits maintained in Bannerghatta biological park in Karnataka state of India

Clinico-pathologic observations of spontaneous hepatic coccidiosis in broiler rabbits maintained in Bannerghatta biological park in Karnataka state of India

Effects of Anticoccidial Drugs on Gross and Histopathological Lesions Caused by Experimental Rabbit Coccidiosis

An Epidemiological Study on Endoparasites of Domestic Rabbits (Oryctolagus cuniculus) in Egypt with Special Reference to Their Health Impact

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