Study on epidemiological trends of canine rabies between2011 and 2014 in Chennai city, South India

Bharathy, Sukumar; Gunaseelan, L.

doi:10.18805/ijar.11424

Cited by 3 publications

(3 citation statements)

References 4 publications

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“…This could be due to greater interaction of this age group with dogs either as pets.A large proportion of dog bite victims were students (33.97%) followed by unskilled groups (30.08%) ( Table 1) again indicating their epidemiological study by (Suraweera et al, 2012) reported 24.3%. Highest victims of dog bites were reported from central part of Chennai as possibly this part Chennai is known to have more number of rabies suspected dogs compared to other parts (Figure 1) which is correlated to the spatial distribution of canine rabies in Chennai city (Figure 2) (Bharathy and Gunaseelan, 2016). Hence people in these areas may be considered to be at a higher risk for dog bites.…”

Section: Resultsmentioning

confidence: 86%

A Cross Sectional Study to Understanding Demographics of Dog Bite Victims Attending Anti Rabies Ward in Chennai City, Tamil Nadu India

Bharathy¹,

Gunaseelan²

2017

Adv. Anim. Vet. Sci.

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| This cross sectional study was conducted by interviewing people attending the anti-rabies ward for post exposure rabies vaccination in a three Government General Hospitals, Chennai city. A total of 256 victims of dog bites from different areas of Chennai were interviewed with a pre tested structured questionnaire after informed verbal consent from victims between April 2013 and April 2014. Out of total 256 victims of dog bite, majority were males (71.87%) in the age group of 11 to 20 years (21.49%). Students outnumbered the general population (33.97%). Higher number of victims of dog bites was reported from Central Chennai. While 46 per cent of victims were bitten by stray dogs,in majority of victims, bite wounds were found in lower portion of the body (59.77%) with major exposure being minor scratches (57.4%). Fifty one per cent of bite victims washed their wounds and 48.44 per cent attended antirabies ward within 24 hours for post exposure prophylaxis. Our findings highlighted that a larger proportion of the bites were provoked, from owned pet dogs with exposures being very minor (scratch) in majority of cases which may not need post bite immunization. There is an urgent need to focus the educational campaigns throughout Chennai city with an effective dog population management combined with strategic immunization program and the effective use of rabies RIG and vaccination in dog bite cases as warranted could help to reduce rabies deaths.

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Section: Resultsmentioning

confidence: 86%

A Cross Sectional Study to Understanding Demographics of Dog Bite Victims Attending Anti Rabies Ward in Chennai City, Tamil Nadu India

Bharathy¹,

Gunaseelan²

2017

Adv. Anim. Vet. Sci.

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“…India is endemic for rabies bearing an annual burden of 35 per cent of the world's human mortality most of which is canine-mediated (W HO, 2018; Bharathy and Gunaseelan, 2016). Except for RABV, no other lyssaviruses have been reported from India (WHO, 2013).…”

Section: Introductionmentioning

confidence: 99%

A Preliminary Study on Bat Lyssavirus in Assam, India

Das,

Dutta,

Boro

et al. 2024

IJAR

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Background: Rabies is a zoonotic disease caused by Lyssavirus of the family Rhabdoviridae, affecting all warm-blooded animals. Although a vast majority of the cases are canine-mediated, many cases of bat-mediated rabies in humans have been documented since the early part of the 20th century. Different lineages of Lyssavirus have been detected in bat populations across Africa, Eurasia and Australia. Although there is no direct evidence of the prevalence of bat Lyssavirus in India thus far, indirect evidences are emerging of late. This has significant public health implications considering the not so infrequent human bat interactions in a country like India. In view of the absence of any systematic surveillance of bat rabies especially in the context of Assam state, a preliminary study was conducted to determine the prevalence of bat lyssavirus in Assam. Methods: 34 brain samples belonging to nine species of bats were collected from fourteen locations in eight districts of Assam, for detection of bat Lyssavirus by Lateral Flow Assay (LFA), Direct Fluorescent Antibody Technique (DFA) and One-step PCR at KVAFSU-CVA Rabies Diagnostic Laboratory, WOAH Rabies Reference Laboratory, Veterinary College, Bengaluru, Karnataka-560 024. Result: None of the samples were positive for lyssavirus indicating absence of an active lyssaviral infection in the representative bat population under study. However, considering the small sample size mere absence of the lyssavirus antigen among bats in the present study does not preclude the pathogen’s presence in bat populations across the state or occurrence in the future, considering the rapidly dynamic state of ecology and environment. Continuous surveillance through One-Health collaboration is essential to monitor the status of bat rabies in India.

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“…. An epidemiologial survey in Chennai, India shows that Rabies is endemic in India(Bharathy and Gunaseelan 2016). Rabies virion, is a bullet shaped, enveloped infectious particle (180 nm x 75 nm in size), having 12 Kb negative sense single-stranded RNA genome, belonging to the Lyssavirus genus of the Rhabdoviridae family and Mononegavirale order.…”

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confidence: 99%

SELEX- Aptamer Technology to Combat Diseases of Animals : Recent Advancement and Future Application: A Review

Mukherjee¹,

Verma²,

Gali³

et al. 2021

IJAR

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Aptamers are ‘nucleic acid antibodies’ that bind to target molecules with high affinity and specificity. The process by which aptamers are selected is called Systematic Evolution of Ligands by Exponential Enrichment (SELEX). A plethora of aptamers have been selected against various targets, such as proteins, cells, microorganisms, chemical compounds, etc. Technical progress in the aspects of high throughput sequencing (HTS) technologies, bioinformatics, microfluidics and nanodevices have widened the scope of aptamers to contribute significantly in human as well as veterinary medicine. We have searched the Pubmed database and Google Scholar with the search term ‘aptamer’, ‘SELEX’, ‘animal diseases’. The search results have been categorized into bacterial, viral and protozoal diseases of veterinary importance. Here we have systematically described the strategy used to design aptamers for each disease and also shed light on the future research scope in this area. This article presents a comprehensive and up-to-date review of SELEX-aptamer technology, its modifications, aptamers selected against various animal pathogens, their potential to be applied in the future for diagnostic and therapeutic purposes.

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Study on epidemiological trends of canine rabies between2011 and 2014 in Chennai city, South India

Cited by 3 publications

References 4 publications

A Cross Sectional Study to Understanding Demographics of Dog Bite Victims Attending Anti Rabies Ward in Chennai City, Tamil Nadu India

A Cross Sectional Study to Understanding Demographics of Dog Bite Victims Attending Anti Rabies Ward in Chennai City, Tamil Nadu India

A Preliminary Study on Bat Lyssavirus in Assam, India

SELEX- Aptamer Technology to Combat Diseases of Animals : Recent Advancement and Future Application: A Review

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