Study of vitamin B12 status and the consequential clinico-hematological profile in healthy vegetarian population in Nepal

Paudel, Pramod; Agrawal, Jagdish; Timilsena, Santosh; Subedi, Jyoti

doi:10.3126/jcmc.v7i1.17369

Cited by 3 publications

(1 citation statement)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The most common symptoms that were told by these participants were weakness and fatigue followed by strange sensations like paresthesias. In a similar study by Paudel et al 8 in, paraesthesia in the lower limbs was the commonest complaint followed by fatigue and tiredness. Similarly in the study by Akabwai et al 9 in Uganda, the most frequent clinical symptoms were paraesthesias, forgetfulness and tiredness even after light exertion.…”

Section: Discussionmentioning

confidence: 67%

An FGD Report on Vitamin B12 Deficiency in Medical Professionals.

Keerti¹,

Sharma²,

Sharma³

2019

IJCMR

View full text Add to dashboard Cite

Introduction: Vitamin B12 Deficiency has become an important health concern in the recent times. Acknowledging the health of medical professionals shall improve the health status of the community as they form a classified population of the society. The present study was done with an aim to assess the treatment seeking behavior of the doctors in RNT Medical College, Udaipur who were found deficient in Vitamin B12 levels. Material and methods: Two focused group discussions were conducted in the department of Community Medicine with a strength of 13 and 17 each, few pre-decided questions were asked to the groups by the moderator and answers were reported by the recorder in the form of tally sheets. Results: Maximum doctors were interested in taking Oral treatment by self, most of them were consuming Reverse Osmosis water and most common clinical feature they expressed were weakness and fatigue. Conclusion: Vitamin B12 deficiency is becoming a silent epidemic which needs to be addressed as it is affecting all the groups of the society and thus further large scale multicentric studies are needed to address this issue at the global level.

show abstract

Section: Discussionmentioning

confidence: 67%

An FGD Report on Vitamin B12 Deficiency in Medical Professionals.

Keerti¹,

Sharma²,

Sharma³

2019

IJCMR

View full text Add to dashboard Cite

show abstract

Study of Clinical and Haematological Profile of Vitamin b12 Deficiency and to Check Response to Vitamin b12 Therapy

Aher,

Navghare,

Zawar

2024

VJIM

View full text Add to dashboard Cite

Objectives: Vitamin B 12 (cobalamin) deficiency has been a known clinical entity for long time. Average Indian diet is deficient in vitamin B12. Deficiency of vitamin is associated with a wide spectrum of haematologic and neuropsychiatric disorders that can often be reversed by early diagnosis and prompt treatment. Diagnosis is easy and treatment ids cheap. Hence, we conducted this study to find patterns of presentation in patients with vitamin B12 deficiency with haematological profile and to check response to therapy. Material and Methods: A longitudinal study was conducted between September 2016 and November 2018 in the Department of Medicine at Government Medical College, Nagpur, India. One hundred patients whose serum vitamin B12 level was <250 pg/mL were included in the study. Results: Mean vitamin B12 level in patients was 162.64 ± 43.31 pg/mL. Most of patients were male and deficiency was common among vegetarians. History of alcoholism was present in 41% of patients. The most common complaint was fatigue present in 87% of patients. Most common neuropsychiatric complaint was tingling and numbness (14%). Most common sign elicited was pallor in 96% of patients while icterus and knuckle hyperpigmentation was present in 57% and 74% of patients, respectively. Mean haemoglobin (Hb) among cases was 6.09 ± 2.21 g/dL. After treatment, all the patients showed a dramatic response in Hb level, mean corpuscular volume, red cell distribution width and mean platelet volume. Conclusion: Deficiency of vitamin B12 is associated with plethora of clinical manifestations. Males, alcoholics and vegetarians are at risk. Early treatment halts late complications.

show abstract

Prevalence and Clinical Spectrum of Vitamin B-12 Deficiency in A Cohort of patient Presenting with Neurological Disorders in Tertiary Care Hospital of Rajasthan

Avasthi

Sharma²,

Soni

2023

AJNER

View full text Add to dashboard Cite

Introduction:Vitamin B-12 is an important nutrient that the body uses to serve as a cofactor in many main cell reactions. Cobalamin, in combination with folate, is necessary for DNA synthesis in cells that undergo rapid turnover, such as haematopoietic and enteric lining cells. Increased homocysteine, reduced methionine, and impaired tetrahydrofolate formation are the physiological effects of either of the above nutrient’s deficiency.1 Material and Methods: Quantitative research approach will be adopted in current research study, Non experimental descriptive research design will be used in this study. Research study for this study was Neurological OPD and hospitalize patient in Mahatma Gandhi Hospital, Jaipur. Sample size will be calculated with appropriate statistical method after pilot study and purposive sampling technique. 400 sample use for this study. Result: Prevalence of neurological disorder due to vitamin B-12 deficiency was13.75% of participant were have mild deficiency of neurological disorder due to vitamin B-12 Deficiency, 66.75% of participant were have moderate deficiency of neurological disorder due to vitamin B-12 Deficiency and 19.50% of participant were have severe deficiency of neurological disorder due to vitamin B-12 Deficiency. These findings caution against identification of patient suffering from vitamin B-12 deficiencies. Discussion: Present studies assess the prevalence and clinical spectrum of vitamin B-12 deficiency in a cohort of patient presenting with neurological disorders in tertiary care hospital of Rajasthan.”

show abstract

Study of vitamin B12 status and the consequential clinico-hematological profile in healthy vegetarian population in Nepal

Cited by 3 publications

References 20 publications

An FGD Report on Vitamin B12 Deficiency in Medical Professionals.

An FGD Report on Vitamin B12 Deficiency in Medical Professionals.

Study of Clinical and Haematological Profile of Vitamin b12 Deficiency and to Check Response to Vitamin b12 Therapy

Prevalence and Clinical Spectrum of Vitamin B-12 Deficiency in A Cohort of patient Presenting with Neurological Disorders in Tertiary Care Hospital of Rajasthan

Contact Info

Product

Resources

About