Study of Ventilator-Associated Pneumonia in a Pediatric Intensive Care Unit

Abstract

Frequency of VAP was 6.03 % with neuromuscular disease, histamine-2 receptor blockers, tracheostomy and positive blood culture being risk factors for VAP.

Ventilator-Associated Pneumonia in Pediatric Intensive Care Unit: Correspondence

“…The microbiological data on the culture of endotracheal aspirates (ETA) was just given as an additional information but was not used by us to mandatorily diagnose VAP. We agree with the editorial commentary that the endotracheal aspirates (ETA) may not truly reflect the organisms causing VAP [1,2]. This is also corroborated by the fact that ETA were positive in 8 out of 15 episodes of VAP and were also positive in patients without VAP (21 cultures positive) in our study (please see Table 2 of our study) [2].…”

“…We agree with the editorial commentary that the endotracheal aspirates (ETA) may not truly reflect the organisms causing VAP [1,2]. This is also corroborated by the fact that ETA were positive in 8 out of 15 episodes of VAP and were also positive in patients without VAP (21 cultures positive) in our study (please see Table 2 of our study) [2]. Thus we wish to strongly refute the statement from the editorial commentary that ETA was the method used by us in the diagnosis of VAP.…”

“…To the Editor : We thank Gnanaguru et al for their informative editorial commentary based on our recent article entitled BStudy of ventilator-associated pneumonia in a Pediatric Intensive Care Unit^published in the Indian Journal of Pediatrics [1,2]. However, we wish to clarify on certain issues raised in the editorial commentary and place on record our point of view.…”

“…Also, as stated in the editorial commentary, the interpretation that our incidence of VAP was less (than other Indian studies) because of the use of microbiological criteria as mandatory in the diagnosis of VAP is also incorrect. As stated in the methods section of our manuscript, we strictly used the Center for Disease Control and Prevention-CDC / NNIS criteria for the diagnosis of 15 episodes on VAP in our study (the CDC / NNIS criteria have been given in the appendix of our original paper) [2]. The microbiological data on the culture of endotracheal aspirates (ETA) was just given as an additional information but was not used by us to mandatorily diagnose VAP.…”

Comparative study of incidence, risk factors, etiological agents and outcome of early and late ventilator associated pneumonia in paediatric intensive care unit at a tertiary care centre

“…[4][5][6] Incidence of late VAP reported in literature is as high as 63.5%. 7 According to data published by the National Nosocomial Infection Surveillance System (NNIS) program sponsored by the Centre for Disease Control and Prevention (CDC), VAP rates in PICU oscillate from 1.4 to 7 episodes per 1,000 ventilator days.…”